洗必泰敷料治疗在PICC局部感染护理中的效果研究[摘要]目的探?洗必泰敷料治疗在经外周静脉置入中心静脉导管（peripherallyinsertedcentralcatheter，PICC）局部感染护理中的效果。方法选取2013年12月～2015年12月期间在我院确诊治疗的PICC相关性局部感染患者100例，依据随机数表法随机分为洗必泰组和碘伏组，每组50例，碘伏组患者给予碘伏湿敷换药治疗，洗必泰组患者给予洗必泰敷料换药治疗，采用酶联免疫吸附法（enzyme-linkedimmunosorbent，ELISA）检测血清降钙素原（proclacitonin，PCT）、C反应蛋白（c-reactiveprotein，CRP）水平，统计分析所有患者治疗疗效、换药次数、导管留置和治愈时间及治疗前后血清PCT、CRP、白细胞计数（whitebloodcellcount，WBC）水平。结果洗必泰组患者治疗有效率明显高于碘伏组，差异有统计学意义（P<0.05）；洗必泰组患者换药次数和治愈时间明显短于碘伏组，前者导管留置时间明显长于后者，差异有统计学意义（P<0.05）；洗必泰组患者治疗后血清PCT、CRP、WBC水平明显低于碘伏组，差异有统计学意义（P<0.05）。结论洗必泰敷料治疗可有效提高PICC相关性局部感染患者的治疗疗效，能够有效改善机体的炎症状态和减少换药次数，且可有效延长导管留置时间，值得临床作进一步推广。[关键词]洗必泰敷料；经外周静脉置入中心静脉导管；局部感染；导管留置时间[]R473.73[文献标识码]B[]1673-9701（2016）34-0153-04StudyontheeffectofchlorhexidinedressinginPICClocalinfectionnursingYUSuqinGUOHaizhenDepartmentofGeneralOncology，HangzhouCancerHospital，Hangzhou310002，China[Abstract]ObjectiveToinvestigatetheeffectofchlorhexidinedressingonlocalinfectionnursingbyperipherallyinsertedcentralcatheters（PICC）.Methods100patientswithPICCinourhospitalfromDecember2013toDecember2015wereselected.Accordingtotherandomnumbertablemethod，theywererandomlydividedintochlorhexidinegroupandiodophorgroup，with50patientsineachgroup.Thepatientsintheiodophorgroupweregiveniodophorwetdressingtreatment，andthepatientsinthechlorhexidinegroupweregivenchlorhexidinedressingtreatment.Thelevelsofserumprocalcitonin（PCT）andc-reactiveprotein（CRP）weredetectedbyenzyme-linkedimmunosorbentassay（ELISA），andthecurativeeffects，numberofdressing，catheterretentiontimeandhealingtime，andthelevelsofserumPCT，CRPandwhitebloodcellcount（WBC）beforeandafterthetreatmentwerestatisticallyanalyzed.ResultsTheeffectiverateoftreatmentinthechlorhexidinegroupwassignificantlyhigherthanthatintheiodophorgroup，andthedifferencewasstatisticallysignificant（P<0.05）；thetimeofdressingandhealingtimeinthechlorhexidinegroupweresignificantlyshorterthanthoseintheiodophorgroup，andthecatheterretentiontimeoftheformerwassignificantlylongerthanthelatter.Thedifferencewas---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---statisticallysignificant（P<0.05）；thelevelsofserumPCT，CRPandWBCweresignificantlylowerinthechlorhexidinegroupthanintheiodophorgroup，andthedifferenceswerestatisticallysignificant（P<0.05）.ConclusionThetreatmentofchlorhexidinedressingcaneffectivelyimprovetheefficacyofthetreatmentofPICC-relatedlocalinfection.Itcaneffectivelyimprovetheinflammationofthebodyandreducethenumberofdressing，andcaneffectivelyprolongthecatheterretentiontime，whichisworthyoffurtherclinicalpromotion.[Keywords]Chlorhexidinedressing；Centralvenouscatheterviaperipheralvein；Localinfection；Catheterretentiontime经外周静脉穿刺中心静脉导管（PICC）是一种从周围静脉导入且末端位于中心静脉的深静脉置管技术，为肿瘤患者提供了一条安全、无痛、便捷的输液通路，因其操作简单、安全、导管留置时间长等特点而被广泛应用于临床，...