81casesofsenilevaginitistreatmentofcompoundChinesemedicinesuppositoryOf:BaihuiLingXuGuoqiangZhaoyuepingmaonthedistantXuZhixiDuyaoWuXiumin[Keywords]senilevaginitisKeywords:Chinesemedicine,extracts;suppositories;senilevaginitis0IntroductionWomennaturalmenopause,bilateraloophorectomyorirradiationcastration,ovarianfunctionrecession,lackofestrogeninthebodysusceptibletosenilevaginitis[1].Estradioltreatment,butoftensideeffects[2],wedevelopedThetraditionalChinesemedicine(Angelica,Cnidium,flavescens,berberineextractvaginalsuppositories,senilevaginitisasfollows.1Materialsandmethods1.1MaterialsofChineseherbalmedicinepurchasedfromlerentangKaifengstores,thetheUmbelliferaesnakebedfortheidentifiedCnidiumCnidiummonnieri(L.cusson.DriedripefruitofSophoraSophoraSophoraflavescensAit.Legumesroot,AngelicafortheUmbelliferaeXingAnBaizhiAngelicaedahurca(etHoor.f.theFischBenthroot,Coptisproduction.theHunanYiyang1greasechemicalplantRanunculusplantsCoptisrhizomesofCoptisChinensisFranch.36semi-syntheticfattyacidglyceridestaketheabovemedicineCnidium300g,Sophora100g,theAngelica100g,Coptis300g,addwater5000mLsoakedinboilingwaterfor30minafterchangethetextgentlyfor30minfiltering,thenthedregssoakincoldwaterfor30minutes,accordingtothelawandfryfiltered,mixedwith1frieddrugsolution.mixturepiecemealHuojianintobrownoil200gplusT-8020mL,glycerol80mLStirmadeofoil-in-wateremulsion,thenstirring,slowlyaddthemeltedsemi-syntheticfattyacidglyceridesmatrix700gfullmixcansoffilmcoolingpackagingServemade4002.5gofthequalityofeachandsuppositoriescontainingChinesemedicineextract0.5gequivalentcrudedrug2g.theourclinicmenopause1aaboveobvioussymptomsofsenilevaginitis(vaginalsecretionsincreased,mostlypaleyellow,individualbloodsamplespurulentvaginaldischarge,genitalitchingorburningsensation,signs(epithelialatrophy,foldsdisappeared,meager,mostofthevaginalmucosacongestionindividualsuperficialulcers,eliminatemold,trichomoniasis,bacterialatotalof81casesofinfectionin2patientswithgynecologicaldiseases.1.2Methods①exposedcervicalsecretionsofthepHwasmeasuredlinevaginalcytology,cervicalsmearasuppositoryintothevaginaafterthedome,day1,10dforacourseoftreatmentduringtreatmentwithoutotherdrugstomaintainwillperineumclean;②efficacyofstandardclinicalcure:symptomsdisappeared,signsandlaboratorytestswerenormal;markedly:themainsignificantimprovementinsymptoms,signsandlaboratorytestseachtwoimproved;effective:themainsymptoms,signsandlaboratorycheckeachonebetter;invalid:nochangebeforeandaftertreatment.postedinthefreepapersDownloadCenterhttp://eng.hi138.comStatisticalanalysis:Wilcoxontestwasused.2Results81patientsafteracourseoftreatment,70patientswerecured,87%;sevencasesmarkedly,accountingfor8%;effectivefourcasesaccountfor5%ofthetotaleffectiveratewas100%aftertwocoursesoftreatment,allcured.inwithdrawal2moafterfollow-upof70cases,sixpatientsrelapsedafteracourseoftreatmenttocure,3accountingfor9%ofthenumberoffollow-upaftertreatmentinpatientswithunderlyingcellsfalloffsignificantlyreducethepHvaluedecreasedsignificantlyreducedvaginalcleanlinessthesuppositorycanimprovepatientswithlocaldiseaseresistance,isalsolikelytoimproveinpatientswithlowestrogenlevels(Table1.courseofmedicationnotoxicity.Table1Chinesemedicinetreatmentofsenilevaginitisafterindicatorsofchange(slightly3DiscussionWepreparedChinesemedicinesuppositoryingredientsflavescens[3],Cnidium,berberine,Angelica,haveawiderangeofanti-bacterial,antitrichomoniasis,anti-tumoreffect.Cnidiumextractonmiceestrogen,folliclestimulatingdevelopment.References:[1]LiaobaiSong,bow,Boruipre-elderlyfemalerathypothalamic-pituitary-ovarianaxisfunctionchanges[J].FourthMilitaryMedicalUniversity,1997;18(6:501-503.[2]ShiYan,CaiYan,JinYong.Phenolcompound4hasbottomoiltreatmentofsenilevaginitis1046casesofclinicalobservation[J]ChineseJournalofGynecologyandObstetrics,2000;16(10:612.[3]ZHANGYan-jun,summer,MEDICINALIS.Differentiation-inducingeffectofmatrineonSMMC-7721celllines[J]FourthMilitaryMedicalUniversity,1998;19(3:340-343.LinkstofreepapersDownloadCenterhttp://eng.hi138.com5