探讨不同MRI检测方法在评估子宫内膜癌患者深肌层浸润中的临床价【摘要】目的比?^不同核磁共振成像（MRI）检测方法在评估子宫内膜癌患者深肌层浸润中的临床价值。方法50例子宫内膜癌患者，分别对其采用T2加权信号（T2WI）、增强T1加权信号（CET1WI）和弥散加权信号（DWI）等方法行MRI扫描检测，评估深层肌层浸润程度，并将其与手术病理结果进行对比。结果50例子宫内膜癌患者中，34例患者经手术病理证实为有肌层浸润，占68.0%；16例患者经手术病理证实为无肌层浸润，占32.0%。经T2WI检测有肌层浸润的准确性为80.0%，敏感性为88.2%，特异性为62.5%，阳性预测价值为83.3%，阴性预测价值为71.4%；经CET1WI检测有肌层浸润的准确性为78.0%，敏感性为82.4%，特异性为68.8%，阳性预测价值为84.8%，阴性预测价值为64.7%；经DWI检测有肌层浸润的准确性为82.0%，敏感性为91.2%，特异性为62.5%，阳性预测价值为83.8%，阴性预测价值为76.9%；经T2WI和CET1WI联合检测的准确性为90.0%，敏感性为94.1%，特异性为81.3%，阳性预测价值为91.4%，阴性预测价值为86.7%；经T2WI和DWI联合检测的准确性为96.0%，敏感性为97.1%，特异性为93.8%，阳性预测价值为97.1%，阴性预测价值为93.8%。T2WI和DWI联合检测的准确性、敏感性、特异性以及阳性预测价值、阴性预测价值均明显高于其他检测方法，差异均有统计学意义（P<0.05）。结论T2WI和DWI联合检测能够更好的显示子宫内膜癌深肌层浸润程度，可以为临床诊断提供可靠的依据，提高诊断准确率。【关键词】子宫内膜癌；核磁共振成像；深肌层浸润程度；准确性；特异性DOI：10.14163/jki.11-5547/r.2017.05.019InvestigationofclinicalvaluebydifferentMRIdetectionmeasuresinevaluationofdeepmyometrialinvasioninendometrialcancerpatientsZHAOFeng-yu.TielingCountyCentralHospital，Tieling112000，China【Abstract】ObjectiveTocompareclinicalvaluebydifferentmagneticresonanceimaging（MRI）detectionmeasuresinevaluationofdeepmyometrialinvasioninendometrialcancerpatients.MethodsAtotalof50patientswithendometrialcancerallreceivedMRIscanningdetectionbyT2-weightedimaging（T2WI），enhancedT1-weightedimaging（CET1WI）anddiffusionweightedimaging（DWI）.Evaluationwasmadeondeepmyometrialinvasiondegreetocomparewithsurgicalpathologicaloutcome.ResultsAmongthe50patientswithendometrialcancer，therewere34caseswithconfirmedmyometrialinvasionbysurgicalpathology，accountingfor68.0%，and16caseswithoutconfirmedmyometrialinvasionbysurgicalpathology，accountingfor32.0%.T2WIindetectionofmyometrialinvasionshowedaccuracyas80.0%，sensitivityas88.2%，specificityas62.5%，positivepredictivevalueas83.3%，andnegativepredictivevalueas71.4%.CET1WIindetectionofmyometrialinvasionshowedaccuracyas78.0%，sensitivityas82.4%，specificityas68.8%，positivepredictivevalueas84.8%，andnegativepredictivevalueas64.7%.DWIindetectionofmyometrialinvasionshowedaccuracyas82.0%，sensitivityas91.2%，specificityas62.5%，positivepredictivevalueas83.8%，andnegativepredictivevalueas76.9%binationofT2WIandCET1WIindetectionofmyometrialinvasionshowedaccuracyas90.0%，sensitivityas94.1%，specificityas81.3%，positivepredictivevalueas91.4%，andnegativepredictivevalueas86.7%binationofT2WIandDWIindetectionofmyometrialinvasionshowedaccuracyas96.0%，sensitivityas97.1%，specificityas93.8%，positivepredictivevalueas97.1%，andnegativepredictivevalueas93.8%binationofT2WIandDWIhadobviouslyhigheraccuracy，sensitivity，specificity，positivepredictivevalueandnegativepredictivevaluethanothermeasures，andtheirdifferencesallhadstatisticalsignificance（P<0.05）.ConclusionCombineddetectionbyT2WIandDWIcanpreciselyshowdeepmyometrialinvasiondegreeinendometrialcancer.Thismethodcan...