盐酸哌甲酯控释片联合静灵口服液治疗小儿多动症的临床效果【摘要】目的：探?采取盐酸哌甲酯控释片联合静灵口服液治疗小儿多动症的临床效果。方法：选择2014年3月-2017年3月本院收治的小儿多动症患儿74例作为研究对象，家长均愿意配合研究，根据治疗方案不同分为对照组和治疗组。对照组36例采取盐酸哌甲酯控释片治疗，治疗组38例采取盐酸哌甲酯控释片联合静灵口服液治疗。对两组患儿临床效果进行评价，记录不良反应，并测评治疗前后多动症评分，实施统计学分析。结果：治疗组临床总有效率明显高于对照组，不良反应发生率明显低于对照组，差异均有统计学意义（P<0.05）。两组患儿治疗前多动症评分比较，差异无统计学意义（P>0.05），治疗后较治疗前均有下降（P<0.05），且治疗后治疗组明显低于对照组（P<0.05）。结论：小儿多动症采取盐酸哌甲酯控释片联合静灵口服液治疗，可以提高临床疗效，改善多动症评分，而且不良反应少，安全性高，值得在临床中应用。【关键词】小儿；多动症；盐酸哌甲酯控释片；静灵口服液ClinicalEffectofMethylphenidateHydrochlorideControlled-releaseTabletsCombinedwith激nglingOralLiquidonChildrenwithADHD/XIAOZhen，WUWei-zhao.//MedicalInnovationofChina，2017，14（30）：041-043【Abstract】Objective：ToinvestigatetheclinicaleffectofMethylphenidateHydrochlorideControlled-releaseTabletscombinedwith激nglingOralLiquidonchildrenwithADHD.Method：74childrenwithADHDwhowereadmittedtothehospitalfromMarch2014toMarch2017wereselectedasthestudysubjects，parentswerewillingtocooperatedwiththestudy.Theyweredividedintotwogroupsaccordingtodifferenttreatmentprotocols，36casesincontrolgroupweretreatedwithMethylphenidateHydrochlorideControlled-releaseTablets，and38casesintreatmentgroupweretreatedwithMethylphenidateHydrochlorideControlled-releaseTabletscombinedwith激nglingOralLiquid.Theclinicaleffectsofthetwogroupswereevaluated，adversereactionswererecorded，andthescoresofADHDbeforeandaftertreatmentwereevaluatedandstatisticanalysiswascarriedout.Result：Thetotaleffectiverateoftreatmentgroupwassignificantlyhigherthanthatofcontrolgroup，theincidenceofadversereactionswassignificantlylowerthanthatofcontrolgroup，thedifferenceswerestatisticallysignificant（P<0.05）.Beforetreatment，thescoresofADHDwerecomparedbetweentwogroups，thedifferencewasnotstatisticallysignificant（P>0.05），aftertreatment，theADHDscorewaslowerthanthatofbeforetreatment（P<0.05），andthetreatmentgroupwassignificantlylowerthanthatofthecontrolgroup（P<0.05）.Conclusion：ThetreatmentofADHDbyMethylphenidateHydrochlorideControlled-releaseTabletscombinedwith激nglingOralLiquidcanimprovetheclinicalcurativeeffectandimprovethehyperactivityscore，andtheadversereactionislowandthesafetyishigh，whichisworthtobeappliedinclinic.【Keywords】Pediatric；ADHD；MethylphenidateHydrochlorideControlled-releaseTablets；激nglingOralLiquidFirst-author’saddress：XiaolanHospitalAffiliatedtoSouthernMedicalUniversity，Zhongshan528415，Chinadoi：10.3969/j.issn.1674-4985.2017.30.012小儿多动症也叫做注意缺陷多动障碍，是儿童时期比较常见的一种心理行为异常综合征。多动症患儿的智力正常或与正常儿童接近，但在学习、行为及情绪方面有一定缺陷，常有注意力不集中、活动过度与注意时间短、冲动等症状，伴或不伴有品行障碍、适应不良等。本病发病可能和神经解剖、遗传、神经生理、神经递质、环境、家庭等因素有关[1]。盐酸哌甲酯控释片是治疗小儿多动症常用药物，单用疗效一般，近几年研究指出联合静灵口服液治疗可提高疗效[2-4]。为了进一步探讨小儿多动症采取盐酸哌甲酯控释片联合静灵口服液治疗的临床效果，本院对收治的小儿多动症患者74例进行研究，现报道如下。1资...