PKRP与TURP治疗良性前列腺增生的Meta分析中文摘要目的:系统评价经尿道双极等离子前列腺电切术(tTansurcthcralplasmakincticresectionofprostate,PKRP)与经尿道前列腺电切术(transurethralresectionofprostate,TURP)两种手术方式治疗良性前列腺增生的临床综合评价。包括在手术时间、手术出血量、导尿管留置时间、术后膀胱冲洗时间、术后住院时间等治疗效果方面及IPSS、Qmax、QOL评分、RUV有效性指标方面的差异情况。方法:采用电子检索和手工检索对文献进行初检,电子检索数据库包含有中国期刊全文数据库、CENTRAL>Medlinedatabase>Cochrane图书馆和中国循证医学/Cochrane中心数据库(CEBM\CCD)等数据库,检索所有有关PKRP和TURP治疗良性前列腺增牛症的随机对照试验(RCT),检索时间均为建库至2014年1月31日。手工检索《中华泌尿外科学杂志》等3种杂志,纳入采用涉及经尿道双极等离子切除术(transurethendplasmakineticresectionofprostate,PKRP)•经尿道前列腺电切术(transurethralresectionofprostate,TURP)随机对照试验(RCT),数据由两名研究员各自独立提取,纳入研究的方法学质量采用Jadad质量评分标准,运用Cochrane协作网提供的专用Meta分析软件RevMan5.2对统计数据进行分析。结果初检中文文献564篇,外文文献64篇,最终纳入15篇RCT(其中4篇英文,11篇中文)涉及对照统计。Meta分析结果显示,PKRP组在手术时间(min)、术中失血量(niL)、术后持续膀胱冲洗时间(d)和留置导尿时间(d)、术后住院时间(d)、国际前列腺症状评分(IPSS)、最大尿流率(Qmax)等方面好于TURP组,疗效差异有统计学意义;在术后半年残余尿量(RUV)和生活质量指数(QOL)等方而差异没有统计学意义。结论PKRP与TURP治疗良性前列腺增生相比,在手术时间、手术出血量、导尿管留置时间、术后膀胱冲洗时间、术后住院时间、IPSS评分、Qmax等方面较好,在术后半年QOL评分、RUV等有效性方面没有显著性差别。ComparedPKRPwithTURPintreatmentofbenignprostatichyperplasiainmeta-analysisAbstract[Objective】Systematicallyassessthedifferenceoftransurcthcralplasmakincticresectionofprostateandtransurethralresectionofprostateintheteatmentsofbenignprostatichyperplasiaontheoperationtimes,bloodloss,postoperativebladderirrigationtimes,indwellingcathetertimes,hospitalstaytimesafterthesurgery.【Methods]Electronicandmanualsearchesoftheliteraturesearchesconductedinitialinspection,ElectronicretrievaldatabasecontainsPubMed,CENTRAL,ChineseJournalFull-textDatabase,Medlinedatabase,CochraneLibraryandChineseEvidence-BasedMedicine/CochraneCenterdatabase(CEBM\CCD),etc.Retrievealltherandomizedcontrolledtrial(RCT)ofthetreatmentsofbenignprostatichyperplasiabyPKRPandTURP,RetrievaltimesarcthedatabasesbuildingtoJanuary31,2014.Manualsearchesrecently"ChineseJournalofUrology”andotherthreekindsofmagazines.Includedallrandomizedcontrolledtrial(RCT)transuretheralplasmakincticresectionofprostate,andtransurethralresectionofprostate,thedataextractedindependentlybytworesearchers,themethodologicalqualityofincludedstudiesusingtheJadadqualityassessmentcritcria.andmakethedataanalysiswiththesoftwareofRevMan5.2providedbytheCochranecollaborationnetwork・[Results】564Chineseliteraturesand64foreignliteraturesaftertheinitialinspection,eventuallyincluded16RCT(4inEnglish,12inChinese)involvedinthecontrolstatistics.Mcta-analysisshowedthatthedifferencewasstatisticallysignificant.[Conclusion]comparedtotheteatmentsofoperationtimes,bloodloss,postoperativebladderirrigationtimes,indwellingcathetertimes,hospitalstaytimesafterthesurgeryInternationalProstateSymptomScore,Qmax,PKRPisbetterthanTURPforbenignprostatichyperplasia.刖吕良性前列腺增牛是中老年男性共同面对的一个的泌尿系统疾病,它也是引起...