依达拉奉联合醒脑静治疗高血压性脑出血的临床效果［摘要］目的探讨依达拉奉与醒脑静注射液联合应用治疗高血压性脑出血的临床效果。方法选择2014年6月〜2015年6月期间本院内科收治的48例高血压性脑出血患者，随机将其分为观察组和对照组，每组各24例。对照组给予常规高血压性脑出血治疗，包括应用抗菌药物预防感染、脱水，降低颅内压，控制并发症，维持水电解质平衡以及对症支持疗法。观察组在此基础上，给予依达拉奉注射剂30mg加入5%葡萄糖或0.9%氯化钠注射液100ml中静滴，2次/d,14d为1个疗程，醒脑静注射液20ml加入5%葡萄糖或0.9%氯化钠注射液250ml中静滴，1次/d,14d为1个疗程。结果对照组基本治愈8例，好转4例，显著进步4例,进步5例，差5例，治疗总有效率为61.54%；观察组基本治愈13例，好转7例，显著进步4例，进步2例，差0例，治疗总有效率为92.31%,观察组治疗总冇效率明显高于对照组，差异冇统计学意义(P〈0.05)。对照组出现肺部感染2例，泌尿系感染1例；观察组出现肺部感染1例。结论依达拉奉与醒脑静注射液联合应用治疗高血压性脑出血患者可发挥明显的抗炎作用，可有效改善患者脑功能，提高其生存质量，有较好的疗效及安全性。［关键词］依达拉奉；醒脑静；高血压性脑出血［中图分类号］R544.1［文献标识码］A［文章编号］1674-4721(2016)05(a)-0032-03ClinicaleffectofEdaravoneandXingnaojingInjectionintreatinghypertensivecerebralhemorrhageCHENShanDeparmentofCardiovascularMedicine,JiujiangCountyPeoplezsHospitalinJiangxiProvince,Jiujiang332100,China[Abstract]ObjectiveToexploretheclinicaleffectofEdaravoneandXingnaojingInjectionintreatinghypertensivecerebralhemorrhage・Methods48hypertensivecerebralhemorrhagepatientsfromJune2014toJune2015inourhospitalwerecollectedandrandomlydividedintoobservationgroupandcontrolgroup,andeachgroupwas24cases・Patientsincontrolgroupweregivenroutinetreatmentforhypertensivecerebralhemorrhage^antibioticswereusedtopreventinfection,dehydrationwasusedtodecreaseintracranialpressureandcontrolcomplications,waterandelectrolytebalancewasmaintainedandothersymptomaticsupporttherapy.Onthebasisofthat,patientsinobservationgroupwerefurthergivenEdaravoneInjection30mgin5%glucoseor0.9%sodiumchlorideinjection100mlforinjection,twiceadayfor14daysasancourse,andXingnaojingInjection20mlin5%glucoseor0.9%sodiumchlorideinjection250mlforinjection,onceadayfor14daysasancourse.ResultsThenumberofbasiccure,improve,significantprogress,progress,badandthetotaleffectiverateincontrolgroupwasrespectively8,4,4,5,5casesand61.54%,whichwererespectively13,7,4,2,0casesand92.31%,thetotaleffectiverateinobservationgroupwasobvioushigherthanthatincontrolgroupandthedifferencewasstatisticalsignificance(P<0・05)•Therewere2caseswithlunginfectionand1withurinaryinfectionincontrolgroup；only1withlunginfectioninobservationgroup.ConclusionEdaravonecombinedwithXingnaojingInjectionintreatinghypertensivecerebralhemorrhagehasobviousanti-inflammationrole,whichcanimprovethebrainfunctionandenhancethelifequality,withbettereffectsandsafety.
