真武汤合桃红四物汤治疗阳虚血瘀型慢性射血分数降低性心力衰竭的【摘要】目的?^察真武汤合桃红四物汤治疗阳虚血瘀型慢性射血分数降低性心力衰竭的临床疗效。方法110例阳虚血瘀型慢性射血分数降低性心力衰竭患者，按治疗方式不同分为西医组及中西医结合组，每组55例。西医组给予血管紧张素转换酶抑制剂、β-受体阻滞剂、醛固酮受体拮抗剂治疗，中西医结合组在西医组基础上加用真武汤合桃红四物汤治疗。观察两组患者的临床治疗效果，对比两组患者治疗前后左心室射血分数（LVEF）、左室舒张末期内径（LVED）及氨基末端脑利钠肽前体（NT-proBNP）、超敏C反应蛋白（hs-CRP）、胱抑素C（CysC）的水平。结果中西医结合组总有效率为96.4%，其中显效41例，有效12例，无效2例；西医组总有效率为85.5%，其中显效38例，有效9例，无效8例；中西医结合组临床治疗总有效率高于西医组，差异有统计学意义（P<0.05）。治疗前，两组LVEF和LVED比较差异无统计学意义（P>0.05）；治疗后，中西医结合组LVEF高于西医组，LVED低于西医组，差异有统计学意义（P<0.05）。治疗前，两组患者NT-proBNP、hs-CRP、CysC水平比较差异无统计学意义（P>0.05）；治疗后，中西医结合组患者NT-proBNP、hs-CRP、CysC水平低于西医组，差异具有统计学意义（P<0.05）。结论中西医结合治疗阳虚血瘀型慢性射血分数降低性心力衰竭患者具有良好的临床效果，可增加LVEF，改善患者心功能。【关键词】中西医结合；阳虚血瘀型；慢性射血分数；心力衰竭DOI：10.14163/jki.11-5547/r.2018.09.003【Abstract】ObjectiveToobservetheclinicalefficacyofZhenwudecoctionandTaohongSiwudecoctioninthetreatmentofchronicheartfailurewithreducedejectionfractionofYangdeficiencyandbloodstasistype.MethodsAtotalof110chronicheartfailurepatientswithreducedejectionfractionofYangdeficiencyandbloodstasistypeweredividedbydifferenttreatmentmethodsintoWesternmedicinegroupandintegratedtraditionalandWesternmedicinegroup，with55casesineachgroup.Westernmedicinegroupwastreatedwithangiotensinconvertingenzymeinhibitor，β-blocker，aldosteronereceptorantagonist，andintegratedtraditionalandWesternmedicinegroupwastreatedwithZhenwudecoctionandTaohongSiwudecoctiononthebasisofWesternmedicinegroup.Theclinicaltreatmenteffectintwogroupswasobserved，andleftventricularejectionfraction（LVEF），leftventricularend-diastolicdiameter（LVED）andN-terminalpro-brainnatriureticpeptideprecursor（NT-proBNP），highsensitiveCreactiveprotein（hs-CRP）andcystatinC（CysC）levelsbeforeandaftertreatmentbetweenthetwogroups.ResultsIntegratedtraditionalandWesternmedicinegrouphadtotaleffectiverateas96.4%，with41excellentcases，12effectivecasesand2ineffectivecases，whichwere85.5%，38cases，9casesand8casesinWesternmedicinegroup.IntegratedtraditionalandWesternmedicinegrouphadhighertotaleffectiverateofclinicaltreatmentthanWesternmedicinegroup，andthedifferencewasstatisticallysignificant（P<0.05）.Beforetreatment，bothgroupshadnostatisticallysignificantdifferenceinLVEFandLVED（P>0.05）.Aftertreatment，integratedtraditionalandWesternmedicinegrouphadhigherLVEFthanWesternmedicinegroup，andthedifferencewasstatisticallysignificant（P<0.05）.Beforetreatment，bothgroupshadnostatisticallysignificantdifferenceinNT-proBNP，hs-CRPandCysClevel（P>0.05）.Aftertreatment，integratedtraditionalandWesternmedicinegrouphadlowerNT-proBNP，hs-CRPandCysClevelthanWesternmedicinegroup，andthedifferencewasstatisticallysignificant（P<0.05）.ConclusionIntegratedtraditionalandWesternmedicineshowsexcellentclinicaleffectinthetreatmentofchronicheartfailurepatientswithreducedejectionfractionofYangdeficiencyandbloodstasistype，anditcanincreaseL...