高频超声、弹性成像及超声造影对甲状腺良恶性结节的诊断高频超芦、弹性成像及超声造影对甲状腺良恶性结节的诊断［摘要］目的探讨高频超声、弹性成像及超声造影对甲状腺良恶性结节诊断结果情况。方法分析抚顺市中心医院超声科2012年5月〜2014年6月甲状腺结节患者168例的临床资料，分別通过高频超声、弹性成像及超声造影检查，100例良性结节，68例恶性结节。结果高频超声声像图在良恶性鉴别有意义的是病变内部结构、内部回声情况、形状、边界清晰度、周边芮晕规则性、钙化程度(均P〈0.05)o良性结节弹性成像分级I、II级比例(90.0%)明显高于恶性结节(14.7%),良性结节弹性成像分级III、IV级比例(10.0%)明显低于恶性结节(85.3%),实性病变内部结构、低回声、不规则形状、不清晰边界、不规则周边声晕、微钙化声像图特征是区别良恶性重耍的指标，良性甲状腺结节不均匀增强模式比例(10.0%)明显低于恶性结节(75.0%),良性甲状腺结节环形增强(65.0%)明显高于恶性结节(1.5%),差异均有统计学意义(P<0.05)o结论高频超声、弹性成像及超声造影对甲状腺良恶性结节诊断具有重要的价值，可以为甲状腺良恶性结节鉴别诊断提供可靠的理论依据。［关键词］高频超声；弹性成像；超声造影；甲状腺；良恶性结节［中图分类号］R736.1［文献标识码］A［文章编号］1673-7210(2014)10(b)-0076-04Diagnosisofthyroidbenignandmalignantnodulesbyhighfrequencyultrasonic,elastography,ultrasoundcontrastZHANGChenHUShuipingAYUJingZHANGMinDepartmentofUltrasound,FushunCentralHospital,LiaoningProvince,Fushun113008,China［Abstract］ObjectiveToapproachdiagnosisofthyroidbenignandmalignantnodulesbyhighfrequencyultrasonic,elastography,ultrasoundcontrast・MethodsClinicaldataof168caseswiththyroidbenignandmalignantnodulesinDepartmentofUltrasoundinFushunCentralHospitalfromMay2012toJune2014wasobservedbyhighfrequencyultrasonic,elastography,ultrasoundcontrast・Benignnoduleswere100cases,Malignantnoduleswere68cases・ResultsTheidentifymeaningfulofbenignandmalignancyinhighfrequencyultrasonicultrasonographic,whichwasinteriorstructure,echo,shape,boundarydefinition,acoustichalosurroundingtheregularity,calcificationdegree(P<0.05)・TheElasticityimagingclassificationI,IIproportionofbenignnodules(90.0%)washigherthanmalignantnodules(14.7%),theelasticityimagingclassificationIII,IVproportionofbenignnodules(10.0%)washigherthanmalignantnodules(85・3%),internalstructureofsolidlesions,lowecho-level,irregularshape,in-definedboundary,irregularperipheralhalo,microcalcificationsonographicfeatureswereimportantindexindifferencebetweenbenignandmalignant・Thediagnosticobservationofthyroidbenignandmalignantnodulesbyhighfrequencyultrasonic,elastography,ultrasoundcontrastweredifferentbetweenbenignandmalignantimportantindicator・Unevenenhancementpatternofbenignthyroidnodules(10.0%)werelowerthanmalignantnodules(75.0%),annularenhancementofbenignthyroidnodules(65・0%)werehigherthanmalignantnodules(1.5%),thedifferenceswerestatisticallysignificant(P<0.05)・ConclusionThediagnosticobservationofthyroidbenignandmalignantnodulesbyhighfrequencyultrasonic,elastography,ultrasoundcontrasthasanimportantvalue,whichistobeprovidedreliabletheorybasisfordifferentialdiagnosisofthyroidbenignandmalignantnodules・〈！--endprint--X!―startprint-->[Keywords]Highfrequencyultrasonic；Elastography；Ultrasoundcontrast；Thyroid；Benignandmalignantnodules甲状腺结节是目前常见疾病，其患病率呈现明显的增高趋势，甲状腺结节性疾病往往见于女性患者，其男女比例为4：1,其临床症状不明显，大多数是在体检过程中发现［1-2］o甲状腺乳头状癌发病率较低，一般有近80%的乳头状癌患者术后20年生存率可以达到99%,对甲状...