ChinesemedicinetreatmentoffungalotitisexternaclinicalobservationAbstract:Objective:Toobservetheeffectoftheexternalauditorycanaltreatmentefficacyoffungaldisease.Methods:canalfungaldiseasepatients,200caseswererandomlydividedintotreatmentgroupandcontrolgroup,treatmentgroupof100caseswithberberineeardropsearcanal,controlgroupof100caseswitha4%boricacidalcoholcoatedearcanal.therapeuticeffectswereobserved.Results:Thecure80cases,theeffectiveratewas96.0%inthecontrolgroupcured48cases,totaleffectiverate79.5%,thetreatmentgroupwassignificantlybetterthanthecontrolgroup(P<0.05)Conclusion:Chinesemedicineberberineeardropshasgoodantibacterialanti-inflammatoryeffect,asignificanteffect,safe,worthyofpromotionandapplicationinclinicalpractice.Keywords:Coptiseardrops,otitisexterna,fungi,efficacyHigherincidenceoffungalotitisexterna,fungi1easilyinthewarm,moistenvironmentgrowthandreproduction,inthetreatmentbylocaladministrationbasedonthetreatmentoffungalotitisexternashouldbefirstclearedofallfungicanalcrustsandsecretions,trytokeeptheearcanaldry,applypaintorlocallydropswithtopicaldrugs[1]IoutpatientsinceJune2008toJanuary2010usingtraditionalChinesemedicineberberineeardropstotreatfungalotitisexterna100cases,resultsweresatisfactory.nowreportedasfollows.1MaterialsandMethods1.1Generalinformation:thetreatmentgroup,100caseswereoutpatients,atotalof120ears.42malesand56ears,female58cases,64earsinthecontrolgroupof100patients110ears,including44malesand52ears,female56cases,58ears.aged12-58years,mean32.5years,durationofoneweek-8yearsofclinicalmanifestations:areitchyearcanal,canalflowswhenasmallamountofthinsecretionsAnotherexamination:canalseenwithgreyishyelloworwhitemembrane,theformofpowderorfilaments,oracylindricalshapeormassivethicksecretions,thesurfaceofthewhitefungusmoss,remove2themembrane-likeandsecretions.inclusioncriteria[2]①earcanalitching,humid,andoccasionallyatnightitching.③canalcoveringgraymatterorgraypowder,fluffyfungalgrowth.②canalexudateorrednessorswelling.Allpatientswerepositiveforfungalcultureandfungalmicroscopyconfirmed.1.2Treatment:completeremovaloftheexternalauditorycanalmossfirstfilmortubelumpsinthetreatmentgroupwithacottonswabrubbedberberineeardropsearcanal,onceaday,onceevery2weeks,thecontrolgroupwithacottonswabto4%boricacidalcoholrubbedintheearcanal,onceaday,onceeverylweekscontinuetouseoneweekaftersymptomsdisappear,suchasnolongervalid,nolongerusedduringtreatmentwithotherdrugs,tokeeptheearcanaldrycleaning.3monthsaftertreatment,referral,takethecanalpropertysmear-positive.1.3Theevaluationcriteria[4]cure:thesymptomsdisappeared,theearcanalclean,nocongestionorerosion,2timessmearnegative,effective:symptoms,ear3congestionormilderosion,2timessmearnegative,improved:symptoms,signsofimprovementcomparedwithbeforetreatment,butthesmear-positive,invalid:symptomsandsignsofimprovement,smearpositive.healedandcuredbytreatmentiseffective.1.4StatisticalanalysisusingstatisticalsoftwareSPSS14.0statisticalanalysisoftheobtaineddata,countdatausingthex2test,measurementdatausingttest,P<0.05wasconsideredstatisticallysignificant.2ResultsAftertwocoursesoftreatment,bothgroupsshowedsignificanttherapeuticeffect,statisticalresultsareshowninTable1canbeseenfromthetable,thetreatmentgroupcured80cases,0ineffective,thetotaleffectiverate96.0%inthecontrolgrouprecovered48cases,6cases,thetotalefficiencyof79.5%,Comparisonofclinicaleff...