动脉血乳酸、降钙素原及NT-proBNP对体外循环心脏手术患者评估中的应用王琼广东省肇庆市第二人民医院心胸外科，广东肇庆526060［摘要］目的研究动脉血乳酸、降钙素原及NT-proBXl>运用于体外循环心脏手术患者中的评估价值。方法选取我院2017年1月〜2019年4月纳入的65例体外循环心脏手术患者作为研究对象，分别于术后不同时间段进行动脉血乳酸、降钙素原及NT-proBNP水平检测，观察检测结果并分析其在术后评估中的价值。结果所有研究对象经过手术后，其中有62例宿舌，另3例死亡。存活者中发生并发症者有20例，包含消化系统意外事件有5例，其中不明原因腹痛3例，急性肝功能损伤2例：循环系统意外事件4例，其中低心排综合征1例，顽固性高血压2例，心律失常1例：泌尿系统意外事件2例：术后感染7例：神经系统意外事件2例。存活组术后Oh、术后8h、术后Id、术后2d的动脉血乳酸均低于死亡组，而术后8h、术后Id、术后2d的降钙素原及NT-proBNP水平低于死亡组，差异有统计学意义(P<0.05)。木后2d并发症组的动脉血乳酸、降钙素原及NT-proBNP水平均高于未发生并发症组，差异有统计学意义(P<0.05).结论动脉血乳酸、降钙素原及NT-proBNP运用于体外循环心脏手术中具有重要的价值，可准确评仙术后病情变化，对手术风险进行预测，值得临床推广使用。［关键词］NT-proBNP；动脉血乳酸：体外循环心脏手术；降钙素原［中图分类号］R654.2［文献标识码］A［文章编号］2095-0616(2020)11-116-04Applicationofarterialbloodlactate,procalcitoninandNT-proBNPintheevaluationofpatientsundergoingcardiopulmonarybypassWANGQiongDepartmentofCardiothoracicSurgery,SecondPeople'sHospitalofZhaoqing,Guangdong,Zhaoqing526060,China［Abstract］ObjectiveTostudytheevaluationvalueofarterialbloodlactate,procalcitoninandNT-proBNPinpatientsundergoingcardiopulmonarybypass.Methods65patientsundergoingcardiopulmonarybypassenrolledatourhospitalfromJanuary2017toApril2019wereselectedasthestudyobjects.Thelevelsofarterialbloodlactate,procalciioninandNT-proBNPweredeteciedatdifferenttimeperiodsaftersurgery.Thedetectionresultswereobservedandtheirvalueinpostoperativeevaluationwasanalyzed.ResultsAftersurgery,62ofthestudyobjectssurvivedand3died.Amongthesurvivors,therewere20casesofcomplications,including5casesofdigestivesystemaccidents,whereintherewere3casesofunexplainedabdominalpain,and2casesofacuteliverfunctioninjury;therewere4casesofcirculatorysystemaccidents,whereintherewas1caseoflowcardiacoutputsyndrome,2casesofintractablehypertension.and1caseofarrhythmia;therewere2casesofurinarysystemaccidents;therewere7casesofpostoperativeinfection：therewere2casesofnervoussystemaccidents.AtOh,8h,Idand2daftersurgery,thearterialb1oodlactateinthesurvivalgroupwaslowerthanthatinthedeathgroup,whileal8h,1dand2daftersurgery,thelevelsofprocalcitoninandNT-proBNPwere1owerthanthoseinthedeathgroup,withstatisticallysignificantdifference(PV0.05).At2daftersurgery,thelevelsofarterialbloodlactate,procalcitoninandNT-proBNPinthecomplicationgroupwereallhigherthanthoseinthecomplication-freegroup,withstatisticallysignificantdifference(P<0.05).ConclusionTheapplicationofarterialbloodlactate,procalcitoninandNT-proBNPincardiopulmonarybypasshasimportantvalue,whichcanaccuratelyevaluatethechangesinpostoperativeconditionsandpredicttherisksofsurgery,whichisworthyofclinicalpromotionanduse.［Keywords］NT-proBNP;Arterialbloodlactate:Cardiopulmonarybypass;Proca1citonin近几年，我国心脏疾病的患病率日渐升高，而方式。虽然体外循环技术获得了较高的应用价值，体外循环心脏手术随之增加，成为临床常见的治疗但因为手术时间较长、操作较为复杂、创伤较大等表1存活组与死亡组动脉血乳酸、降钙素原及NT-proBNP水平变化...