木香顺气丸加减联合草酸艾司西酚普兰片治疗抑郁症的临床研究[摘要]目的探讨木香顺气丸加减联合草酸艾司西酚普兰片治疗抑郁症的临床效果。方法选取本院2011年12月～2014年2月诊治的抑郁症患者116例，采用数字随机法分为两组，58例患者采用草酸艾司西酚普兰片治疗为对照组，58例患者采用木香顺气丸加减联合草酸艾司西酚普兰片治疗为观察组，采用汉密尔顿抑郁量表（HAMD）评定抑郁状况，采用世界卫生组织生活质量量表（WHOQOL-BREF）评定生活质量，比较两组患者的抑郁情况、生活质量、治疗效果、不良反应情况。结果治疗后，两组患者HAMD评分均显著下降，而生活质量评分均明显增加。观察组患者HAMD评分、不良反应发生率均明显低于对照组，观察组患者生活质量评分、总有效率均明显高于对照组，差异均有统计学意义（P＜0.05）。结论木香顺气丸加减联合草酸艾司西酚普兰片是治疗抑郁症的有效方法，可明显改善患者的抑郁状况，显著提高患者的生活质量，不良反应少且安全性高，值得临床推广使用。[关键词]木香顺气丸加减；草酸艾司西酚普兰片；抑郁症[]R749#8195;#8195;#8195;[文献标识码]B#8195;#8195;#8195;[]2095-0616（2014）08-84-03ClinicalresearchofMuxiangShunqipill#160;combinedwith#160;escitalopramoxalate#160;tabletsin#160;treatmentfordepressionLIU#8195;Yanwu1#8195;#8195;KANG#8195;Zhichen2#8195;#8195;LI#8195;Ying3#8195;#8195;SONG#8195;Yu41.PsychiatricRehabilitation#160;Hospital,Anning,Changchun,Changchun130000,China;2.DepartmentofRecovery,theSecondHospitalof激linUniversity,Changchun130041,China;3.DepartmentofSocialWork,thePeople'sHospitalof激linProvince,Changchun130061,China;4.FacultyofAgriculture,#160;激linUniversity,Changchun130000,China[Abstract]ObjectiveToinvestigateclinicaleffectofMuxiangShunqipill#160;combinedwithescitalopramoxalate#160;tabletsin#160;treatmentfordepression.Methods116patientswithdepressionwereselectedinhospitalfromDecember2011toFebruary2014,whowererandomly#160;dividedintotwogroups.58patientstreatedescitalopramoxalate#160;tabletsascontrolgroup.58patientstreatedMuxiangShunqipill#160;combinedwith#160;escitalopramoxalate#160;tabletsasobservationgroup.DepressionwasevaluatedbyHamiltonDepressionScale#160;(HAMD).Qualityof#160;lifewasevaluatedbyWHO#160;qualityoflifescale#160;(WHOQOL-BREF).Depression,qualityoflife,therapeuticeffect,adversereactionwerecomparedbetweentwogroups.ResultsAftertreatment,#160;HAMDscore#160;significantlydecreasedwhilequalityoflife#160;scoresignificantlyincreasedin#160;twogroups.HAMDscore,incidenceofadversereactionsinobservationgroupweresignificantly#160;lowerthancontrolgroup.Qualityoflifescore,totaleffectiverateinobservationgroupweresignificantlyhigherthancontrolgroup.Differenceswerestatisticallysignificant#160;(P＜0.05).ConclusionMuxiangShunqipill#160;combinedwith#160;escitalopramoxalate#160;tabletsiseffectivemethodin#160;treatmentfordepression,#160;whichcansignificantlyimprovedepression#160;statusandqualityoflife.Thathaslessadversereaction#160;and#160;highsafety,whichisworthyofclinicaluse.[Keywords]MuxiangShunqipill;Escitalopramoxalate#160;tablet;Depression近年来，随着生活节奏的加快和竞争压力的增加，人们的精神压力越来越大，使得抑郁症发病率持续走高，严重威胁着公众的身体健康，影响着患者的预后[1-3]。为了探讨木香顺气丸加减联合草酸艾司西酚普兰片治疗抑郁症的临床效果，本院选取2011年12月～2014年2月诊治的抑郁症患者116例，采用数字随机法分为两组，对照组采用草酸艾司西酚普兰片治疗，观察组采用木香顺气丸加减联合草酸艾司西酚普兰片治疗，针对两组患者的抑郁情况、生活质量、治疗效果、不良反应情况进行对比分析，现报道如下。1#8195;资料与方法1....
