PETCT检测中血糖对脑肝摄取影响的临床应用DOI：10.7504/nk2016010203中图分类号：692文献标识码：A摘要.•目的探讨PET/CT检测中血糖对脑肝摄取影响的临床应用。方法选择2014年3月至2016年1月在我科行PET/CT检测的患者或体检者，排除标准：患有脑部及肝脏恶性肿瘤、严重脑梗或其他中枢神经系统疾病、肝功能不全者及肝脓肿等影响脑组织或肝脏正常摄取者不记入组。木次研宄井193例，以空腹血糖水平高低分三组：血糖正常组、血糖稍高组、血糖较高组，三组患者年龄、性别比例、体重、剂量等临床资料比较，无差异。脑部显像按图像质量由差到好分为四级：0级、1级、2级、3级。结果木次研究对不同空腹血糖水平下的脑部显像规律进行比较，血糖水平较高组的各个级别的百分比与其它两组比较P<0.05,具有统计学意义，近30%的脑组织显影呈0级，随着血糖水平的降低，脑组织显影0级与1级图像比例降低，2、3级图像比例升高，血糖正常组，脑组织显影3级百分比明显高于其他两组，说明脑组织显像图像质量受血糖浓度的影响，随着血糖水平升高脑组织显影图像质量变差，反之，可以得到较高脑部图像质量；随着空腹血糖水平的升高，脑组织对18F-FDG的摄取SUVmax值逐渐降低，其值与血糖值呈反比；肝脏的SUVmax随着空腹血糖浓度的增高而增高。结论血糖浓度能够影响人体脑组织及肝脏等对18F-FDG摄取，因此在行I8F-FDGPET/CT检查前，如何认识和利用这些显像规律变化，对提高18F-FDG显像质量，减少由此造成对肿瘤的误判及漏诊，有一定的临床应用价值。关键词：生理性摄取血糖最大标准摄取值阈值肿瘤PET/CTexaminationofbrainglucoseuptakeinliverClinicalApplicationLIUChun-hai,FENGXiao-wei,WANGHai-dong,LIRei-min,ZHANGYun,CHEN丫ong-jie,DUWen-xia【Abstract】ObjectiveDiscussiononPET/CTexaminationonbrainglucoseuptakeinliverClinicalApplication.MethodsSelectfromMarch2014toJanuary2016inourdepartmentPET/CTdetectionofpatientsorvolunteers，Exclusioncriteria:sufferingfrombrainandlivercancer，severebrainstemorothercentralnervoussystemdisorders,liverdysfunctionandliverabscess，braintissuesofnormalliveruptakewerenotcreditedtothegroup.Inthisstudyatotalof193casestotheleveloffastingbloodglucosedividedintothreegroups:Normalbloodglucosegroup(3.9-6.1):72patients(42male,30female),slightlyhigherglucosegroup(6.2-9.0):76cases(45male,31female)，highglucosegroup(≥9.1):45Li(27male，18female)，clinicaldataofthreegroupsofage,gender，bodyweight,dosage，etc，thedifferencewasnotstatisticallysignificant(P>0.05),ThebrainimagingstudyofthelawunderdifferentfastingbloodglucoselevelbycomparingthepercentageofalllevelsofbloodglucoselevelshighergroupwithothertwogroupsP<0.05,statisticallysignificant，nearly30%ofthedevelopingbraintissuewere0,withlowerbloodsugarlevels，theratiooftheimageofthedevelopingbraintoreduce0level1，level2and3imageratioincreasedbloodsugarnormalbraintissuedevelopinggrade3percentagesignificantlyhigherthantheothertwogroups，theimpactofbloodglucoseconcentrationofbrainimagingbytheimagequality,alongwithelevatedbloodsugarlevelsinbraintissuedevelopedimagequalitydeterioration，onthecontrary，thebraincangetahigherimagequality;withtheelevatedfastingbloodglucoselevels,brainuptakeof18F-FDGSUVmaxvaluegraduallydecreasesitsvalueisinverselyproportionaltobloodglucoselevel；LiverSUVmaxwithincreasedfastingplasmaglucoseconcentrationincreased.Brainimagingbythepoortogoodqualityimageisdividedintofourlevels:0,Level1,Level2andLevel3.ResultsInthefastingbloodglucoselevelunderdifferentmyocardialimaging，alllevelsofhigherconcentrationratioofthegroupwithothertwogroupsP<0.05，statisticallysignificant，nearly80percentoftheheartwallnosignificantdevelopment，withthedecreasein...
