金双歧治疗极低出生体重儿喂养不耐受的观察［摘要］目的探讨双歧杆菌乳杆菌三联活菌片(金双歧)治疗极低出生体重儿喂养不耐受的临床疗效。方法将极低出生体重儿喂养不耐受60例随机分为治疗纟R和对照组，各30例。对照组给予常规对症护理与治疗，治疗组在对照组基础上给予双歧杆菌四联活菌喂奶口服或鼻饲金双歧，干预周期为5do结果经过治疗后，治疗组和对照组的胃潴留和腹胀平均消失时间分别为(2・03±0・36)、(2.36±0.42)d；(5.36±1・11)、(6.00±0・95)d,治疗组的胃潴留和腹胀消失时间均明显少于对照纟fl(均P<0.05)。治疗组和对照组的平均恢复出生体重需要时间和住院天数分别为(8.32±3.63)、(10.26土5.23)d；(16.58土4.23)、(25.36±6.21)d,治疗组的恢复出生体重需要时问和住院天数均明显少于对照组(均P<0.05)。结论金双歧治疗极低出生体重儿喂养不耐受能尽快从静脉营养过度到胃肠营养，加快极低出生体重儿的体重增长，促进胃潴留和腹胀症状的消失，缩短住院时间，值得推广应用。［关键词］金双歧；极低出生体重儿；喂养不耐受［中图分类号］R724［文献标识码］A［文章编号］1673-7210(2012)01(b)-079-02ObservationofJinshuangqiinthetreatmentoffeedingintoleranceofverylowbirthweightinfantsPANGYingchaoWANGZhangxingWUXianglanLUANJingWANGChunTONGYanmeiDepartmentofNeonatology,LonghuaPeople'sHospitalofBao,anDistrietinShenzhenCity,GuangdongProvince,Shenzhen518109,China［Abstract］ObjectiveToinvestigatetheeffectsofLiveCombinedBifidobacteriumandLactobacillusTablets(Jinshuangqi)inthetreatmentoffeedingintoleraneeofverylowbirthweightinfantsMethods60casesofverylowbirthweightinfantswithfeedingintolerancewererandom!ydividedintotreatmentgroupandcontrolgroup,with30casesineachgroup・Thecontrolgroupwasgivenroutinecareandsymptomctictreatment,thetreatmentgroupwasgivenoralViableBifidobacteriumTabletsornasogaslricJinshuangqionthebasisofcontrolgroup,withinterventionperiodof5d・ResultsAftertreatment,thegastricrotenlionandbloatingmeandisappearancetimeinthetreatmentgroupandcontrolgroupwere(2.03±0.36),(2.36±0.42)d;(5.36±1.11),(6.00±0.95)clrespectively,thegastrieretention“ndbloatingdisappearedtimeoftreatmentgroupweresignificantlylessthanthecontrolgroup(P<0.05)・Theaveragetimeofregainingbirthweightandhospitalstayinthetreatmentgroupandcontrolgroupwere(8.32±3.63),(10.26±5.23)cl;(16.58±4.23),(25.36±6.21)clrespectively,theaveragetimeofregainingbirthweightandhospitalstayinthetreatmentgroupweresignifiedntlylessthanthecontrolgroup(allP<0・05).ConclusionJinshuangqiintreatingverylowbirthweightinfantsoffeedingintoleraneecanchangeparenteralnutritionassoonaspossibleintogastrointestinalnutrition,speeduptheweightincreasingofverylowbirthweightinfants,promotethedisappearanceofgastricretentionandbloatingsymptoms,andshorterhospitalstay,whichisworthyofpromotion.［Keywords］Jinshuangqi;Verylowbirthweightinfants;Feedingintoleranee极低出生体重儿是指出生1h内体重不足1500g的新生儿。随着新生儿重症监护病房的发展，急救水平的不断提高，极低出生体重儿存活率越來越高，其生存质量逐渐成为研究重点［1］。但是其体内备器官发冇不成熟，尤其是消化系统，极易发生各种并发症，但随着围生医学技术的迅速发展，极低出生体重儿的存活率逐年提高，其中合理喂养在极低出生体重儿存活和以后正常的生长发冇中起着重要作用［2］。笔者将对我院极低出生体重儿开奶后添加双歧杆菌乳杆菌三联活菌片(商品名：金双歧)治疗的疗效进行系统研究，以探讨出治疗极低出生体重儿喂养不I耐受的更好方法。现报道如下：1资料与方法1.1一般资料2010年5月〜2011年8月在我院新生儿科住院的体重在1.0〜2.5kg的早产儿中，选取有腹胀、胃潴留、呕吐等喂养不耐受表现者60例(所有病例无合并症)...