ChineseandWesternmedicineincompatibilityofAbstract:IntegrativedevelopmentandhowcombinedwithWesternmedicineinordertoenhancetheefficacyandavoidadversereactions,thepurposeofrationaldruguse,hasbeenplaguedclinicians,clinicalpharmacistresearchpaperwillnotappropriatedrugsoccurredinWesternmedicinecombinedwiththechangeofthephysicalandchemicalproperties,pharmacologicalchange,resultinginthereductionofdrugtreatment,increasedtoxicitysummingupthediscussion.Keywords:adversedrugreactionsreasonablecompatibilityofdrugsafetyIntroduction:ChineseandWesternmedicinecompatibilityhasbecomeameansoftoday’sclinical,inwesternmedicinecompatibility,thiscanimprovetheefficacy,reducedtoxicity,butsomereducetheefficacyorproducetoxicsideeffects,theapplicationanddevelopmentofChinesemedicinehasalonghistory,afteralongpracticeacertainunderstanding,totalcompatibilitybanofChinese---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---andWesternmedicineinclinicalpaidinsufficientattentionto,andoftenthereisthephenomenonofirrationaluseofdrugs.nowdiscusstheincompatibilityofChineseandWesternmedicinefrompharmacologicalchemistryandpharmacology.First,thephysicalandchemicalpropertieschangeleadingtoreducedefficacyorincreasedtoxicity1,theformationoftheprecipitatecontainstanninBurnet,pomegranaterind,gall,rhubarbandothertraditionalChinesemedicineaswellasMaren,cholereticpieceproprietaryChinesemedicinewithwesternmedicinepreparationsassociatedwithchange:itsphysicalandchemicalpropertiessuchastetracycline,erythromycinandotherglycosides,alkaloidsephedrine,atropine,etc.,andferroussaltformulations,sodiumbicarbonateformulationsassociatedwithprecipitationaffectabsorption.2toformcomplexescontainquercetinBupleurum,mulberryleaves,Huai激ao,,andpreparationscontainingtheseherbswithwesternmedicinecontaining---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---variousmetalionsformcomplexesaffectabsorption.3,pHcombinedalkalinewesternmedicineandfiveignorantchild,LigustrumlucidumacidicChinesemedicineandoxygenalumina,aminophylline,calcinedkeel,calcinedoyster,borax,alkalineChinesemedicinewithpepsinmixture,acetylsalicylicacidandotheracidicwesternmedicinewillplayinreactiontoreducedefficacyorevenlosetheirefficacy.Second,pharmacologicalchangesleadingtoreducedefficacyorincreasedtoxicityPharmacokineticchange(1borax,cuttlebone,corrugatedsub,saponinsandotheralkalineChinesemedicineanditspreparationwithpropranolol,chlorpromazine,ferroussulfateassociatedwithitsabsorptiondecreasedwithquinine,chloroquine,doxycycline,neostigminecombinationwillmakeitfromtheurine,promptinglowerplasmaconcentration,andthequinidineassociatedwiththedischargetoreduce,increaseinthebloodconcentrationofleadpoisoning.---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---(2alkalinetraditionalChinesemedicine,suchasborax,calcinedoyster,sourineacidificationdrugsdissociationincreased,excretionrate,thedurationofactionandlowerintensity.(The3Westernmedicinecompatibility,differentdrugplasmaproteinbindingrate,sothattheplasmaconcentrationofthedrugvaries,thusaffectingitstissuebinding.,SuchastraditionalChinesemedicinecontainingtannincompoundsincombinationwithsulfadrugs,leadingtobloodandtheincreaseintheconcentrationofsulfadrugsintheliver,severetoxichepatitisoccurs.(4urinepHaffectdrugreabsorption,acidifiedoralkalizedfluids,thusaffectingexcretionofthedrug.Shu...