高龄患者HCG日LH值与体外受精胚胎移植结局的关系【摘要】目的探讨高龄患者绒毛膜促性腺激素（HCG）H的黄体生成素（L1I）水平与体外受精胚胎移植（IVFET）治疗结局的关系。方法回顾分析2009年1月至2014年12月女方年龄238周岁，在柳州市妇幼保健院生殖中心接受长方案促排卵治疗370个新鲜移植周期，统计软件作图分析LH值与宫内妊娠率关系，根据SPSS统计软件的系统聚类分析分为A、B、C、D共4组。比较4组患者的年龄、不孕年限、窦卵泡数、降调天数、Gn总量、Gn天数、基础激素、HCG日子宫内膜厚度、内膜类型、获卵数、成熟卵数、移植胚胎个数、移植胚胎优胚率、临床妊娠率、流产率、抱婴回家率。结果根据SPSS统计软件作图结果，妊娠率随着HCG日LH值的增加先增高后降低。4组患者年龄、1ICG日子宫内膜厚度、移植胚胎数、移植优胚率、流产率差异无统计学意义（P>0.05）,B组与D组比较妊娠率、抱婴回家率差异有统计学意义（P<0.008）o结论高龄患者辅助生殖新鲜移植妊娠率随着HCG日LH值的增加而先增高后降低，HCGHLH值在0.76-1.77之间可获得较好临床妊娠率和抱婴回家率。【关键词】年龄；辅助生殖；黄体生成素；妊娠结局中图分类号：R321.1文献标识码：ADOI:---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---10.3969/j.issn.10031383.2015.05.011RelationshipbetweenLHvalueinHCGdayandoutcomeofinvitrofertilizationandembryotransferinagedpatients[HJ1][HJ]XULixiang,TANGYongmei,WEILihong,QINZuxing,WEIJihong(LiuzhouMaternalandChildHospital,Liuzhou535000,Guangxi,Chirm)[HJ1][HJ]【Abstract]ObjectiveToinvestigatetherelationshipbetweenluteinizinghormone(LIDlevelinhumanchorionicgonadotropin(1ICG)dayandthetreatmentoutcomeofinvitrofertilizationandembryotransfer(IVFET)ofagedpatients・MethodsRetrospectiveanalysiswasperformedinwomenwhoaged38orabove,receiving370freshtransfercyclesoflongprotocolovulationinductioninReproductiveCenterofMaternalandChildHea1thHospitalofLiuzhoufromJanuary,2009toDecember,2014.StatisticalanalysisandgraphingwasusedtodealwiththerelationshipbetweenLHlevelanduterinepregnancyrate,andallthewomenweredividedintogroupA,groupB,groupCandgroupDaccordingtohierarchicalclusteranalysisinSPSSstatisticalsoftware・Then,ages,durationofinfertility,antralfolliclecount,daysoffallingtone,Gnamount,Gndays,foundationhormone,endometrialthicknessinHCGday,endometrialpattern,numbersofretrievedoocytes,numbersofmaturationoocytosaswellasnumbersofembryotransfer,highqualifiedembryorateofembryotransfer,clini---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---calpregnancyrate,abortionrateandtakehomebabyratewerecomparedbetweengroups・ResultsResultsofSPSSstatisticalanalysisandgraphingshowedthatpregnancyratefirstincreasedandthendecreasedwiththeincreaseofLHvalueinHCGday.Differenceofages,endometrialthicknessinHCGday,numbersofembryotransfer,highqualifiedembryorateofembryotransferandabortionrateinthe4groupswasnotstatisticallysignificant(P>0.05)・Inaddition,differeneeofclinicalpregnancyrateandtakchomcbabyrateofgroupBwasstatisticallysignificantwhencomparingtogroupD(PConclusionTheclinicalpregnancyrateofwomanwithassistedreproductionfreshtransplantationfirstincreaseandthendecreasewiththeincreaseofLHvalueinHCGday.WhentheLHvalueinHCGdayisbetween0.76~1.77,pationtscanobtainbetterclinicalpregnancyrateandtakehomebabyrate.[Keywords]age；assistedreproduction；LH；pregnancyoutcome年龄是影响辅助生殖治疗的重要因素之一，随着年龄的增加，妊娠率逐渐下降，有研究表明女方年龄>35岁，妊娠率呈明显下降趋势。但大多研究都以女方年龄35岁为界，并没有具体分析35岁至40岁之间各个年龄层的妊娠率变化，...