甲状旁腺腺瘤的超声诊断及其引导下经皮射频消融治疗的效果分析摘要：目的分析甲状旁腺腺癌患者的超声影像学特点，并采用超声引导下经皮射频消融治疗甲状旁腺腺癌，探讨其临床疗效。方法：选取我院2012年2月-2020年3月期间收治的80例甲状旁腺腺瘤患者作为研究对象，采用彩色多普勒超声仪对患者进行扫描检查，分析其检出效果。采用超声引导下经皮射频消融治疗实验对象，分析患者的甲状旁腺激素和血钙水平变化及预后。结果81个肿瘤病灶中包括甲状旁腺右叶下27个、左叶下25个、左叶上15个、右叶上9个和锁骨关节下方气管4个，其中超声诊断出右叶下24个、左叶下22个、左叶上10个、右叶上5个和锁骨关节下方气管2个，彩色超声扫描检查总检出率为77.78%（63/81）。超声检出甲状腺下极病灶46个（56.79%），高于上极的15个，二者检出率比较差异均有统计学意义(P<0.05)。所有81例经超声引导下经皮射频消融治疗患者均未发现术口血肿或针道出血情况，其中3例患者出现声音嘶哑情况，但均在4d内自行恢复，且甲状旁腺激素随时间的延长而显著下降（P＜0.05），血钙术后各时点均显著低于术前（P＜0.05）。结论：彩色多普勒超声诊断可定位甲状旁腺腺瘤病灶，且在超声引导下经皮射频消融治疗下可改善甲状旁腺激素、血钙水平，且无严重并发症。关键词：甲状旁腺腺瘤；超声；经皮射频消融术；应用价值中图分类号：文献标识码：UltrasoundindiagnosisofparathyroidadenomaandanalysisoftheeffectsofpercutaneousradiofrequencyablationLvJingmin,ZhangJunhua,ShenJiangchaoFunctionaldepartmentofShijiazhuangHospitaloftraditionalChinesemedicineShijiazhuangHebei050000Abstract：ObjectiveToanalyzethecharacteristicsofultrasoundimagingofpatientswithparathyroidadenocarcinoma,andtouseultrasound-guidedpercutaneousradiofrequencyablationtotreatparathyroidadenocarcinoma,andtoexploreitsclinicalefficacy.MethodsEightypatientswithparathyroidadenomaadmittedinourhospitalfromFebruary2012toMarch2020wereselectedastheresearchsubjects.ColorDopplerultrasoundwasusedtoscanthepatientsandanalyzethedetectioneffect.Ultrasound-guidedpercutaneousradiofrequencyablationwasusedtoanalyzethechangesofparathyroidhormoneandserumcalciumlevelsandtheirprognosis.Results81tumorlesionsincludingparathyroidrightlobeunder27,25undertheleftlobe,leftlobeonthe15,therightlobeon9andcollarbonejointbelowthetrachea,whichundertheultrasonicdiagnosisofrightlobe24,22undertheleftlobe,leftlobeonten,fiveontherightlobeandcollarbonejointtracheabelow2,colorultrasoundscanoveralldetectionratewas77.78%(63/81).46(56.79%)hypothyroidlesionsweredetectedbyultrasound,whichwashigherthanthatintheupperpole15,andthedifferenceindetectionratebetweenthetwowasstatisticallysignificant(P<0.05).All81casesbyultrasoundguidedpercutaneousradiofrequencyablationtherapyhasnotbeenfoundinpatientswithbleedingmouthhematomaorneedle,threeofthepatientsappearedvoicehoarse,butallwithin4drecoverybyoneself,andparathyroidhormonewiththeextensionoftimedecreasedsignificantly(P<0.05),postoperativebloodcalciumeachpointweresignificantlylowerthanbefore(P<0.05).Conclusion:ColorDopplerultrasounddiagnosiscanlocatethelesionsofparathyroidadenoma,andultrasound-guidedpercutaneousradiofrequencyablationcanimprovethelevelsofparathyroidhormoneandbloodcalciumwithoutseriouscomplications.Keywords：Parathyroidadenoma;Ultrasound;Percutaneousradiofrequencyablation;Applicationvalue甲状旁腺是人体重要的内分泌腺体，主细胞分泌的甲状旁腺激素具有升高血钙和降低血磷的作用[1]。甲状旁腺腺体体积小、位置隐蔽、变异程度大，因此临床上极易发生漏诊误诊[2]。目前，CT、MRI影像检查方法由于目睹分辨率等局限性在临床使用上具有局限性，且影像显示率均低于高频彩色多普勒...