新生儿心内直视手术的体外循环管理[作者简介]李小兵,男,主治医师,本科,从事心血管外科体外循环。[通讯作者]张儒舫,男,主任医师,教授,硕士学位,硕士生导师;研究方向:小儿心血管外科疾病。[摘要]目的:总结36例新生儿心内直视手术的体外循环(cardiopulmonarybypass,CPB)管理经验。方法:回顾性总结2009年2月~2011年1月新生儿心内直视手术36例,其中,男28例,女8例;年龄3~28d,平均(22.07±6.76)d;体重2.0~5.0kg,平均(3.60±0.47)kg。其中常温2例,浅低温14例,中低温11例,深低温低流量4例,深低温停循环选择性脑灌注5例。深低温患儿应用pH稳态、甲基强的松龙和甘露醇。CPB中监测平均动脉压心率静脉混合血氧饱和度尿量、鼻咽温、肛温和中心静脉压。全组心肌保护采用高钾晶体液停跳液。术中和停CPB后应用平衡超滤与改良超滤。结果:全组患儿CPB转---本文来源于网络,仅供参考,勿照抄,如有侵权请联系删除---流时间40~158min,平均(80.19±35.43)min;主动脉阻断时间0~85min,平均(45.02±22.03)min;所有病例均自动复跳,5例发生并发症,1例死亡,其余均痊愈出院。结论:CPB中应用个体化管理和采用综合措施是新生儿心内直视手术成功的保障。[关键词]新生儿;体外循环;心内直视手术[]R654.1[文献标识码]B[]1673-7210(2011)07(c)-135-03Managementofcardiopulmonarybypassforopen-heartsurgeryinneonatesLIXiaobing,ZHANGRufang,GENGLinDepartmentofCardialSurgery,ShanghaiChildren'sHospital,Children'sHospitalAffiliatedtoShanghai激aoTongUniversity,Shanghai200040,China[Abstract]Objective:Tosummarycardiopulmonarybypass(CPB)managementinopen-heartsurgeryof36neonates.Methods:36casesneonatalwithopen-heartoperationfromJanuary2009toFebruary2011werecollected,28malesand8females.Theagesofthepatientswere3----本文来源于网络,仅供参考,勿照抄,如有侵权请联系删除---28(22.07±6.76)days,andthebodyweightswere2.0-5.0(3.60±0.47)kg,2caseswithcommontemperature,14caseswithmildhypothermia,11caseswithmoderatehypothermia,4caseswithdeephypothermialowflow,5caseswithdeephypothermiacirculatoryarrest(DHCA)andselectioncerebralperfusion.DeephypothermianeonatesweremanagedbypH-statbloodgas,methylprednisoloneandmannito.DuringCPBMonitormeanarterialbloodpressure,heartrate,venousadmixturesaturationofbloodoxygen,urinaryvolume,nasalpharynxtemperature,rectaltemperatureandcentralvenouspressure.Allthecaseswereappliedwithcoldhighpotassiumcrystalmyocardialpreservation.BalanceuhrafihrateandmodifieduhrafihratewereappliedduringtheoperationandafterstoppingtheCPB.Results:ThemeanCPBtimewere40-158(80.19±35.43)minutes,andaorticcrossclampingtimewere0-85(45.02±22.03)minutes.Theheartbeatrecoveredspontaneouslyi---本文来源于网络,仅供参考,勿照抄,如有侵权请联系删除---nallpatients.1casediedand5casesappearedcomplications,theotherswereallrecoverywell.Conclusion:ItistheguaranteeofsuccesstointensifycombinationmeasuresandindividuationmanagementsofCPBforneonateopen-heartoperation.[Keywords]Neonate;Cardiopulmonarybypass;Open-heartoperation我院2009年2月~2011年1月在体外循环(cardiopulmonarybypass,CPB)下行新生儿心内直视手术36例,术后出现并发症5例,死亡1例,现将CPB管理经验介绍如下:1资料与方法1.1一般资料全组共36例,其中,男28例,女8例;年龄3~28d,平均(22.07±6.76)d;体重2.0~5.0kg,平均(3.60±0.47)kg。1.2病种分类完全性大动脉错位6例;主动脉弓离断3例;主动脉弓缩窄2例;完全型肺静脉畸形引流5例;完全型房室间隔缺损4例;室间隔缺损合并房间隔缺损12例;室间隔缺损合并动脉导管未闭或卵圆孔未闭2例;肺动脉瓣狭窄合并房间隔缺损2例。1.3方法全组采用静吸复合麻醉,术中监测心电图、平...