探讨关节镜清理术联合低浓度臭氧腔内注射治疗膝骨关节炎的临床疗【摘要】目的：观察关节镜清理术联合低浓度臭氧腔内注射治疗膝骨关节炎（OA）的临床疗效。方法：选择2013年1月-2015年12月在本院进行OA治疗的患者67例，按照来诊时间排序，序列号为单号患者作为观察组，共计34例，序列号为双号患者作为对照组，共计33例。对照组患者行膝关节镜清理术，观察组行膝关节镜清理术联合低浓度臭氧腔内注射治疗。观察治疗前、治疗2周和随诊3个月患者膝关节功能情况和临床疗效。结果：两组患者治疗前ISOA评分比较，差异无统计学意义（P>0.05）；治疗2周两组患者评分均明显降低（P<0.05），但两组比较差异无统计学意义（P>0.05）；随诊3个月，对照组患者评分明显高于观察组（P<0.05）。治疗前两组AKSS评分比较，差异无统计学意义（P>0.05）；治疗2周两组AKSS评分均明显升高，但观察组升高更加明显（P<0.05）；随诊3个月两组AKSS评分比较，差异有统计学意义（P<0.05）。治疗2周，观察组优良率为91.18%，对照组为87.88%，差异无统计学意义（P>0.05）。随诊3个月，观察组优良率为97.06%，对照组为75.76%，观察组优良率明显高于对照组（P<0.05）。结论：关节镜清理术联合低浓度臭氧腔内注射治疗OA临床疗效显著，尤其是远期疗效更为明显。【关键词】关节镜清理术；低浓度臭氧腔内注射；膝骨关节炎【Abstract】Objective：Toobservetheclinicaleffectofarthroscopicdebridementcombinedwithlowconcentrationozoneinjectioninthetreatmentofkneeosteoarthritis（OA）.Method：Atotalof67caseswithOA，whichadmittedinourhospitalfromJanuary2013toDecember2015，wereselectedastheresearchobjectsandaccordingtothefollow-uporting.Oddnumberserialnumberpatientsastheobservationgroup，atotalof34cases，evenserialnumberpatientsasthecontrolgroup，atotalof33cases.Patientsinthecontrolgroupweretreatedwitharthroscopicdebridement.Patientsintheobservationgroupwereunderwentarthroscopicdebridementcombinedwithlowconcentrationozoneinjectiontreatment.Beforeand2weeksaftertreatmentand3monthsfollow-upofpatientswithkneejointfunctionandclinicalcurativeeffectsoftwogroupswasobserved.Result：TherewerenosignificantdifferenceinISOAscoresbetweentwogroupsbeforetreatmentand2weeksaftertreatment（P>0.05）.Thepatientswerefollowedupfor3months，andthecontrolgroupwassignificantlyhigherthanthatoftheobservationgroup（P<0.05）.TherewasnosignificantdifferenceinAKSSscorebetweentwogroupsbeforetreatment（P>0.05）.After2weekstreatment，thescoresofpatientsincreasedsignificantly，buttheobservationgroupwassignificantlyhigher，andthescoresweresignificantlydifferentbetweentwogroupsafter3monthsfollow-up.After2weeksoftreatment，theexcellentandgoodrateoftheobservationgroupwas91.18%，thecontrolgroupwas87.88%，andtherewasnosignificantdifference（P>0.05）.After3monthsfollow-up，theexcellentrateoftheobservationgroupwas97.06%，thecontrolgroupwas75.76%，theexcellentrateoftheobservationgroupwassignificantlyhigherthanthatofthecontrolgroup，andthedifferencewasstatisticallysignificant（P<0.05）.Conclusion：ArthroscopicdebridementcombinedwithlowconcentrationozoneinjectioninthetreatmentofOAhasasignificantclinicalefficacy，especiallylong-termeffectismoreobvious.【Keywords】Arthroscopicdebridement；Lowconcentrationozoneinjection；KneeosteoarthritisFirst-author’saddress：GuangzhouCityIntegratedTraditionalChineseandWesternMedicineHospital，Guangzhou510800，Chinadoi：10.3969/j.issn.1674-4985.2016.24.008膝骨关节炎（OA）是临床常见的关节疾病，该疾病以关节软骨变性和丢失以及关节边缘和软骨下骨质再生为特征的慢性关节炎疾病，在老年人群中发病率较高[1]。相关文献报道，1/2的60岁以上人群在X线片上具...