急性脑梗塞中医痰证与颈动脉粥样硬化的相关性研究【摘要】目的：探究急性脑梗塞中医痰证与颈动脉粥样硬化的相关性。方法：采用回顾性分析的方法，将2014年6月—2015年6月在我院接受治疗的120例急性脑梗塞颈动脉粥样硬化患者的临床资料进行研究分析，并按照中医辨证分型标准进行分组，痰证组64例，非痰正组56例，并将同期在我院体检的60名健康人作为对照组，对这三组的IMT指标进行综合评价，并对痰证组与非痰证组的血脂水平、颈动脉粥样硬化发生率以及颈动脉斑块性质进行综合分析。结果：脑梗死痰证和非痰证患者TG、TC、LDL均升高,与对照组比较差异较大（P<0.05）,其中痰证患者TG、TC、LDL高于非痰证患者(P<0.05);痰证患者和非痰证患者HDL均降低,与正常对照组比较有统计学意义(P<0.05),而痰证和非痰证患者HDL含量比较无统计学意义（P<0.05）。痰证组与非痰证组的颈动脉内中膜厚度出现增厚，IMT指标明显高于对照组（P<0.05），痰证组与非痰证组IMT指标组间比较差异明显（P<0.05），统计学有意义；痰证组与非痰证组斑块发生率差异不大（P>0.05），无统计学意义；且痰证组的不稳定斑块占71.2%，非痰证组不稳定斑块仅为32.6%，差异较大（P<0.05），统计学有意义。结论：中医痰证与颈动脉内膜增厚密切相关，颈动脉粥样硬化斑块是导致急性脑梗塞的高危因素，必须加强早期预防。【关键词】急性脑梗塞；中医痰证；颈动脉粥样硬化；相关性【中图分类号】R242【文献标识码】A【文章编号】2095-1752（2017）01-0045-02AcutecerebralinfarctionofTCMphlegmsyndromeandthecorrelationofcarotidarteryatherosclerosisstudyPanXiaoming,YangRuiling.TheSecondPeople'sHospitalAffiliatedtoFujianUniversityofTraditionalChineseMedicineEncephalopathy,FujianFuzhou,350000,China【Abstract】ObjectiveToexploretheacutecerebralinfarctionofTCMphlegmsyndromeandthecorrelationofcarotidatherosclerosis.MethodsAretrospectiveanalysismethod,fromJune2014toJune2014inourhospitaltreated120casesofacutecerebralinfarctionpatientswithcarotidatherosclerosisresearchanalysis,andaccordingtothestandardoftraditionalChinesemedicinegroup,64casesofphlegmsyndromegroup,thephlegmisgroupof56cases,andwillbeinthesameperiodinourhospitalcheck-upof60healthypeopleascontrolgroup,thecomprehensiveevaluationofthesethreegroupsofIMTindicatorsofphlegmsyndromeandphlegmsyndromegroupoflipidlevelsandincidenceofcarotidatherosclerosisandcarotidplaquespropertiesofcomprehensiveanalysis.ResultsThecerebralinfarctionpatientswithphlegmsyndromeandphlegmTG,TCandLDL,differencescomparedwithcontrols(P<0.05),ofwhichthephlegmsyndromeinpatientswithTG,TC,LDLishigherthanthephlegmsyndromepatients(P<0.05);PatientswithphlegmsyndromeandphlegmsyndromepatientsHDLarelower,comparedwithnormalcontrolgroupwasstatisticallysignificant(P<0.05),andpatientswithphlegmsyndromeandphlegmHDLlevelscomparedwithnostatisticalsignificance(P<0.05).Ofphlegmsyndromeandphlegmsyndromegroupappearedthickenedcarotidintima-mediathickness,IMTindicatorsaresignificantlyhigherthancontrolgroup(P<0.05),phlegmsyndromeandphlegmsyndromegroupcomparingdifferencesbetweenIMTindexgroupsignificantly(P<0.05),statisticallysignificant;Incidenceofphlegmsyndromeandphlegmsyndromegroupplaquesdifference(P>0.05),nostatisticalsignificance;Unstableplaquesandphlegmsyndromegroup(71.2%),unstableplaquesofphlegmsyndromegroupwasonly32.6%,thedifferences(P<0.05),statisticallysignificant.ConclusionTCMphlegmsyndromeiscloselyrelatedtothecarotidarteryintimalthickeningandcarotidatheroscleroticplaquesisthehighriskfactorsofacutecerebralinfarction,andearlypreventionmustbestrengthened.【Keywords】Acutecerebralinfarction;TCMphlegmsyndrome;Carotidatherosclerosis;The...