基于《素问·咳论》的咳类疾病诊疗网络构建梁元钰吕晓东庞立健董野王佳然张浩洋史雁南盛野Summary目的：对《素问·咳论》所载咳类疾病进行本体网络构建，实现咳类疾病的病因病机、临床表现和治疗穴位间关系的可视化表达，辅助厘清咳类疾病的临床诊疗体系。方法：基于《素问·咳论》原文提取节点和边，构建咳类疾病诊疗网络数据库后，导入Gephi0.9.2软件中进行复杂网络分析。依次进行统计、排序、分割等外观处理，最终以网络图的形式具象化展示咳类疾病的诊疗关系。结果：建立含有76个节点的节点库及含有167条边（244次逻辑关系）的边库，并据此绘制出咳类疾病诊疗网络图。该网络以五脏六腑咳为主体，“肺”“胃”节点的加权度及节点连接的边的权重均高居前列，“寒”在病因节点中加权度较高，“太渊”“足三里”在治疗穴位节点中加权度较高。结论：咳是肺之本症，但五脏六腑皆可犯肺作咳。“聚于胃，关于肺”是对咳类疾病病机的高度概括，临床诊疗中应重视“气之本”肺和“五脏之本”胃。治疗时应当重视太渊和足三里2个穴位。同时，根据治未病理论，应注意既病防变，预防疾病向表里之腑和三焦传变。Key咳;网络;素问·咳论;节点;边;Gephi软件;聚于胃，关于肺;五脏六腑皆令人咳AbstractObjective：ToconstructontologynetworkforcoughbasedonSuwenKelun，andvisualizetheexpressionoftheetiology，pathogenesis，clinicalmanifestations，andtherapeuticacupointsofcough.Methods：ExtractednodesandedgesbasedontheoriginaltextofSuwenKelunwereextracted，thedatabasefordiagnosisandtreatmentofcoughwasconstructed，andthenweimporteditintoGephi0.9.2softwaretoperformcomplexnetworkdiagram.Andweconductedappearanceprocessingsuchasstatistics，sorting，andsegmentation.Finally，thenetworkdiagramwasformedtoconcretelyshowtherelationshipbetweendiagnosisandtreatmentofcoughbynetworkdiagram.Results：Thenodedatabasewith76nodesandtheedgedatabasewith167edges（244timesoflogicalrelationship）wereestablished.Basedonthis，wedrawanetworkdiagramofthediagnosisandtreatmentofcoughdiseases.Thenetworkwasmainlycomposedoffiveinternalorganscoughsandthesixholloworganscoughs.Theweightdegreeofthe‘lungand‘stomachnodesandtheweightsoftheirconnectededgeswerebothattheforefront.Theweightdegreeof‘coldwashighinthenodesaboutthecause，and‘Taiyuan（LU9）and‘Zusanli（ST36）werehighinthenodesaboutthetherapeuticpoints.Conclusion：Coughistheoriginaldiseaseofthelung，butallthevisceracancausecough.“Gatheredinthestomachandconnectedwiththelung”highlygeneralizesthepathogenesisofcough.Inclinicaldiagnosisandtreatment，wemustpayattentiontothelung，“rootofqi”，andthestomach，“rootoffivezangviscera”.Inthetreatment，wemustalsopayattentiontoTaiyuan（LU9）andZusanli（ST36）.Moreover，basedonthepreventivetreatmenttheory，weneedtonoticethediseasedevelopmentandtransmission，aswellaspreventdiseasesfromspreadingtoothervisceraandthesanjiao.KeywordsCough;Network;SuwenKelun;Nodes;Edges;Gephisoftware;Gatheredinthestomach;Visceraleadingtocough中圖分类号：R282：Adoi：10.3969/j.issn.1673-7202.2021.14.022《黄帝内经》是中国现存最早的中医古籍，富含中国传统哲思，非一时一人之作，以黄帝与岐伯对话的形式，记录了古代先民与疾病斗争的经验，被誉为“治病的法书”[1-2]。《黄帝内经》奠定了中医学生理、病理、诊断以及治疗的认识基础，对临床疾病诊治有着重要的指导意义。我们以《素问·咳论》原文为基础，对其所载的咳类疾病进行本体网络构建——由节点（Node）和边（Edge）两部分构成[3]。节点是构成网络的基本单元，边是连接节点的各种链路，代表节点间的逻辑关系[4-5]。节点与边的组合，将抽象的文字语句变换成更易理解和观测的图形，形象描述出文字间的内在关系及关联性[6]，更清晰、有效地具象化...