双侧去骨瓣减压术在双侧不对称性重型颅脑损伤中的临床效果研究[摘要]目的探讨双侧去骨瓣减压术对双侧不对称性重型颅脑损伤的临床治疗效果。方法选择2008年4月〜2011年12月浙江省宁波市第一医院收治的双侧不对称性重型颅脑损伤患者61例为研究对象,随机分为观察组31例,对照组30例。观察组采用双侧去骨瓣减压术,对照组采用单侧标准外伤大骨瓣手术。治疗3个月后患者均行格拉斯哥预后(GOS)评估,比较两组患者术中急性脑组织膨出及术后切口疝发生率、G0S评分及并发症情况。结果①治疗后,观察组术中急性脑组织膨出、术后切口疝发生率均明显低于对照组(9.7%、50.0%比12.9%、53.3%),差异均有统计学意义(均P0.05)o③观察组术后并发症发生率明显低于对照组(19.4%比50.0%),差异有统计学意义(P<0.05)o结论双侧去骨瓣减压术治疗双侧不对称性重型颅脑损伤,其术中并发症发生率及病死率较低,治疗效果及术后预后较好,值得临床推广使用。[关键词]双侧去骨瓣减压术;单侧标准外伤大骨瓣术;双侧不对称性重型颅脑损伤[]R651.15[文献标识码]A[]1673-7210(2014)02(b)-0050-03ClinicalresearchofbilateraldecompressivecraniectomyintreatingbilateralasymmetricalseverecraniocerebralinjuryFEIBinglLING激e21.TheFirstHospitalofNingboCity,Zhe激angProvince,Ningbo315000,China;2.DepartmentofClinicalLaboratory,HuangyanHospitalAffiliatedtoWenzhouMedicalUniversity,Zhe激angProvince,Huangyan318020,China[Abstract]ObjectiveToinvestigatetheclinicalefficacyofbilateraldecompressivecraniectomyinthetreatmentofbilateralasymmetricalseverecraniocerebralinjury.Methods61patientswithbilateralasymmetricalseverecraniocerebralinjurytreatedintheFirstHospitalofNingboCityfromApril2008toDecember2011wereselectedandrandomlydividedintotwogroups.30patientsincontrolgroupand31patientsinobservationgroup,patientsinobservationgroupweretreatedwithbilateraldecompressivecraniectomy,andpatientsincontrolgroupweretreatedwithunilateralstandardlargetraumacraniotomy.TheGlasgowoutcomescore(GOS)ofallpatientsinbothgroupswasevaluated3monthsaftertreatment,theoccurrencerateofintraoperativeacutebraintissuebulgingandpostoperativeincisionherniabetweenthetwogroupswerecompared;GOSscoresandcoinplicationwereobserved.Results①Aftertreatment,incidenceofacuteintraoperativeencephaloceleandincidenceofpostoperativeincisionalherniaofobservationgrouppatientsweresignificantly1owerthanthoseofcontrolgroup(9.7%,50.0%vs12.9%,53.3%),thedifferenceswerestatisticallysignificant(allP0.05).(3)Complicationoccurrencerateofobservationgroupwaslowerthanthatofcontrolgroup(19.4%vs50.0%),thedifferenceswerestatisticallysignificant(allP[Keywords]Bilateraldecompressivecraniectomy;Unilateralstandardlargetraumacraniotomy;Bilateralasyminetricalseverecraniocerebralinjury现代社会交通领域和建筑领域是各种意外事故的高发之处,其中双侧不对称性重型颅脑损伤是人身伤害中的急危重症,因常常得不到及时的救治,患者的病死率较高[1-4]o手术是双侧不对称性重型颅脑损伤治疗首选,救治及时,可有效较低患者病死率,降低后遗症发生率[5-6]o目前临床常用手术方法主要有伤情重侧去骨瓣减压术、单侧标准外伤大骨瓣减压术、双侧去骨瓣减压术等[7-9]o双侧去骨瓣减压术是近年来的新型技术,临床应用效果显著。为了探讨此项技术在治疗双侧不对称性重型颅脑损伤中的效果,本研究对双侧不对称性重型颅脑损伤患者采用双侧去骨瓣减压术治疗,并与其他手术方法进行比较,现将结果总结报道如下:1资料与方法1.1一般资料选择2008年4月〜2011年12月浙江省宁波市第一医院(以下简称“我院”)收治的双侧不对称性重型颅脑损伤61例患者为研究对象,患者年龄21〜63岁,平均(45.7±10.1)岁,其中男52例,女9例。致伤原因包括:47例车祸损伤患者,14例高坠伤患者。所...