罗哌卡因局部浸润用于显微内镜腰椎间盘切除术后镇痛中国医院药学杂志2008年第28卷第18期ChinHospPharmJ,20(J8Se—p,Vol28—,No.18鼻炎具有很好的疗效,其治疗效果具有时间及剂量依赖.另外,不良反应的发生率则明显低于皮下注射,因此具有良好的安全性.并且使用方便,尤其对于儿童患者.因此,可以在临床上广泛使用.参考文献:r1]中华耳鼻咽喉头颈外科杂志编辑委员会中华医学会耳鼻咽喉[2]E33科分会.变应性鼻炎的诊治原则和推荐方案(2004年,兰州)_J].中华耳鼻咽喉头颈外科杂志,2005,4O(3):166167.NuhogluY,OzumutSS,O政法emirM,eta1.Sublingualimmunotherapytohousedustmiteinpediatricpatientswithallergicrhinitisandasthma:aretrospectiveanalysisofclinicalcourseovera3-yearfollow-upperiodEJ].激nvestigAllergolClinIm—munol,2007,17(6):375378.MauroM,RusselloM,IncorvaiaG,eta1parisonofeffica一[4][5]E6]?1575?cy,safetyandimmunologiceffectsofsubcutaneousandsublin—gualimmunotherapyinbirchpollinosis:arandomizedstudy].AllergImmunol(Paris),2007,Apr,39(4):119—122.BrimnesJ.KildsgaardJ,JacobiH,eta1.Sublingualimmuno—therapyreducesallergicsymptomsinamousemodelofrhinitis口].ClinExpAllergy,2007,Apr,37(4):488～497.IaGruttaS,ArenaA,口AnneoWR,eta1.Evaluationoftheantiinflammatoryandclinica1effectsofsublingualirnmunother—apywithcarbamylatedallergoidinallergicasthmawithorwithoutrhinitis[J~.AllergImmunol(Paris),2007,39(2):40—---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---44.CoxL.Sublingualimmunotherapyinpediatricallergicrhinitisandasthma:efficacy,safety,andpracticalconsiderations[J].CurrAllergyAsthmaRep,2007,7(6):410—420.[收稿日期32008—03—25罗哌卡因局部浸润用于显微内镜腰椎间盘切除术后镇痛戎利民,蔡道章,董健文,刘斌,史德海(中山大学附属第三医院骨科,广东广州510630)[摘要]目的:评价罗哌卡因切口周围局部浸润在显微内镜腰椎间盘髓核摘除术后镇痛中的作用.方法:83例行显微内镜腰椎间盘髓核摘除术患者随机分成2组,A组(=43)手术开始前以().75盐酸罗哌卡因10mI于切口周围肌层和皮下局部浸润;B组(=40)手术开始前以().9生理盐水10H于切I1’周围肌层和皮下局部浸润.对手术后患者的疼痛指数,阿片类镇痛药物使用量以及切口愈合情况等进行统计观察.结果:A组患者的结果明显优于B组,A组患者术后疼痛反应轻,阿片类镇痛药物使用量少,胃肠道反应发生率低,住院时间更短.所有患者未出现切口愈合不良等并发症.结论:罗哌卡因切口周围局部浸润对于缓解显微内镜腰椎间盘髓核摘除术后疼痛具有优良的效果,能明显缩短患者术后恢复的时间,值得临床推广使用.[关键词]显微内镜腰椎间盘髓核摘除术;罗哌卡因;超前镇痛[]R199[文献标识码]A[]1001—5213(2I】08)18-157503Effectoflocaltissueinfiltrationwithropivacaineonpainaftermicro-endoscopiclumbardiscec-tomyRONGLirain,CAIDao—zhang,DONG激an-wen,LIUbin,SHIDe-hai(DepartmentofOrthopedics.theyeAffiliatedHospitalofSunYat—senUniversity,GuangdongGuangzhou510630.China)AJnCT:OBJECTIVEToinvestigatethepreemptiveanalgesiceffectofropivacaineinfiltrationatincisioninmicro-endo—scopiclumbardiscectomy.METHODS83casesofmicro-endoscopiclumbardiscectomywererandomlyallocatedto2grouPsasfollows:GroupA(n=43)had10mL0.75ropivacaineinjectedintotheparavertebralmusclesandsubcutaneoustissuesjustbeforewoundincision;GroupB(40)received10mL0.9salineatthesesites.Vitalsigns,postoperativepainscores.woundhealingandopioiddrugusagewererecorded.RESULTSGroupAtreatedwithropivacaine(bypreincisionwoundinfil—tration)showedsignificantlybetterresultsthangroupBformostparameters.PatientsingroupApracticedlesspainexperi—ence,hadloweropioidrequirementsaftersurgery,lowerincidencesofnausea,andshorterhospitalstays.Noneo...