中西医结合治疗幽门螺杆菌相关性慢性糜烂性胃炎的临床观察【摘要】目的：探讨中医辨证治疗幽门螺杆菌相关性慢性糜烂性胃炎的临床疗效及应用价值。方法:选取2010年3月-2013年3月笔者所在医院收治的94例幽门螺杆菌相关性慢性糜烂性胃炎患者，按照随机数字表法将其分为观察组和对照组，各47例。对照组给予常规西医治疗，观察组在对照组基础上给予中医辨证治疗，观察比较两组患者的临床疗效、幽门螺杆菌根除情况及胃镜疗效。结果：经治疗后，观察组的治疗总有效率93.6%(44/47)明显高于对照组的76.6%(36/47),差异有统计学意义(字2=5.37,P=0.02)o观察组的Hp转阴率95.7%(45/47)明显高于对照组W83.0%(39/47),差异有统计学意义(字2=4.03,P=0.04)o观察组的胃镜检查总有效率97.9%(46/47)明显高于对照组的83.0%(39/47),差异有统计学意义(字2=4.42,P=0.04)o结论：采用自拟疏肝和胃饮辨证治疗伴幽门螺杆菌感染慢性糜烂性胃炎临床疗效较好，值得临床进一步推广使用。【关键词】疏肝和胃饮；慢性糜烂性胃炎；幽门螺杆菌；中西结合中图分类号R573.3文献标识码B文章编号1674-6805(2015)2-0015-03TheClinicalObservationofIntegrativeChineseandWesternMedicineintheTreatmentofHelicobacterPylori-AssociatedChronicErosiveGastritis/XIEXian-you.//ChineseandForeignMedicalResearch,2015,13(2)：15-17[Abstract】Objective：ToinvestigatetheclinicalefficacyandapplicationvalueofTCMdifferentiationinthetreatmentofhelicobacterpylori-associatedchronicerosivegastritis.Method：Ninety-fourpatientswithhelicobacterpylori-associatedchronicerosivegastriUsinourhospitalfromMarch2010toMarch2013wereselected，theyweredividedintotheobservationgroupandthecontrolgroupaccordingtotherandomnumbertablemethod,47casesineachgroup.ThecontrolgroupwastreatedwithconventionalWesternmedicine,andtheobservationgroupwastreatedwithTCMdifferentiationonthebasisofcon-trolgroup.Theclinicalefficacy,helicobacterpylorieradica-tionsituationandgastroscopiceffectbetweenthetwogroupswereobservedandcompared.Result：Thetotaleffectiverateoftreatmentinobservationgroupwas93.6%(44/47),itwassignificantlyhigherthan76.6%(36/47)inthecontrolgroup,thediffereneewasstatisticallysigrHficant(字2=5.37,P=0.02).Thenegativeconversionratioofhe-licobacterpyloriinobservationgroupwas95.7%(45/47),itwassignificantlyhigherthan83.0%(39/47)inthecontrolgroup,thediffereneewasstatisticallysignifi-cant(字2=4.03,P=0.04).Thegastroscopytotaleffectiverateofobservationgroupwas97.9%(46/47),itwassignifi-cantlyhigherthan83.0%(39/47)inthecontrolgroup,thediffereneewasstatisticallysign讦icant(字2=4.42,P=0.04).Conclusion：Theclinicalefficacyofself-designeddrinkofsoothingtheliverandharmonizingstomachinthetreatmentofchronicerosivegastritisasso-ciatedwithhelicobacterpyloriinfectionisgoodandworthfurtherclinicalpromotionandapplication.【Keywords】Drinkofsoothingtheliverandhar-monizingstomach；Chronicerosivegastritis；Helicobac-terpylori；IntegrativeChineseandWesternMedicineFirst-author'saddress：ThePeople"sHospitalofJianghuaCounty,Jianghua425500,Chinadoi：10.14033/j.cnki.cfmr.2015.02.007慢性糜烂性胃炎是介于慢性浅表性胃炎和消化性溃疡之间的一种临床常见的消化系统疾病，在临床上有很高的发病率。有研究显示，在慢性糜烂性胃炎患者中，幽门螺杆菌（Hp）的阳性率达95%以上，与糜烂性胃炎反复发作有直接关联⑴。目前对于慢性糜烂性胃炎的治疗，尚无统一的治疗方法。近年来釆用质子泵抑制剂（PPI）和抗菌素为主导的三联疗法为公认治疗Hp相关性胃病的有效办法，Hp的根除率有明显提高，但慢性糜烂性胃炎复发率仍较高［2］。为了寻求更有效的治疗方法，笔者所在医院对幽门螺杆菌相关性慢性糜烂性胃炎患者釆用配合自拟疏肝和胃饮辨证治疗，...