中药饮片合理用药软件知识库构建思路探讨周鹏凌霄刘瑞新李学林张博桂新景---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---R95;R969.3文献标志码A1001-0408（2021）10-1272-05---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---DOI10.6039/j.issn.1001-0408.2021.10.19摘要目的：为中药饮片合理用药软件知识库的构建和软件开发提供参考。方法：查阅近年来合理用药软件和中药饮片合理用药方面的文献，分析中药饮片合理用药的临床特点与现有合理用药软件在中药饮片合理用药检测方面的特点、不足，梳理、归纳总结中药饮片合理用药软件知识库构建的整体思路、核心內容及难点。结果与结论：中药饮片的临床应用以“辨证施治”为主要依据，体现辨证、治法、选方与用药的统一，故对于中药饮片临床应用合理性的考量不能一味地模仿化学药的评价方式。目前的合理用药软件整体设计未能基于中医药理论体系，在中药饮片合理用药审查方面尚不够全面、成熟，且缺少能满足中药饮片合理用药要求的知识库。因此，应以中医药理论体系为指导，构建一套能满足中药饮片“理法方药”使用一致性评价要求的知识库，其内容应该包括患者信息收集、疾病及证型等相关知识库建设、中药饮片炮制品的选择、临证加减、中药饮片品种遴选禁忌、配伍禁忌、联合应用中成药或化学药、中药饮片用药剂量、处方每剂的总剂量及药味数量、特殊煎煮药物、用药方法及给药频次等。中药饮片合理用药软件的开发仍存在疾病及证型等相关知识库建设和临证加减的合理性判定困难等难点。关键词中药饮片;合理用药;辨证施治;合理用药软件;知识库ExplorationontheConstructionIdeasofSoftwareKnowledgeBaseforRationalUseofTCMDecoctionPiecesZHOUPeng1，LINGXiao1，LIURuixin1，LIXuelin1，2，ZHANGBo1，GUIXin激ng1（1.Dept.ofPharmacy，theFirstAffiliatedHospitalofHenanUniversityofTCM，Zhengzhou450000，China;2.ZhengzhouZhongshengIndustrialGroupCo.，Ltd.，Zhengzhou450001，China）ABSTRACTOBJECTIVE：Toprovidereferencefortheconstructionandsoftwaredevelopmentofknowledge---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---baseforrationaluseofTCMdecoctionpieces.METHODS：ByreviewingtheliteraturesonrationaldrugusesoftwareandTCMdecoctionpiecesinrecentyears，theclinicalcharacteristicsofrationaldruguseofTCMdecoctionpiecesaswellasthecharacteristicsandshortcomingsofexistingrationaldrugusesoftwareinthedetectionofrationaldruguseofTCMdecoctionpieceswereanalyzed，andthecorecontentsanddifficultiesintheconstructionofknowledgebaseofrationaldrugusesoftwareofTCMdecoctionpiecesweresummarized.RESULTSCONCLUSIONS：ClinicalapplicationofTCMdecoctionpieceswasmainlybasedon“syndromedifferentiation”，whichreflectedtheunityofdialectics，treatment，prescriptionselectionandmedication.Therefore，theconsiderationoftherationalityofclinicaluseofTCMdecoctionpiecescouldnotblindlyimitatetheevaluationmethodofchemicalmedicine.CurrentrationaldrugusesoftwarewasnotbasedonthetheoreticalsystemoftraditionalChinesemedicine，anditwasnotcomprehensiveandmatureintheaspectofrationaldrugusereviewofTCMdecoctionpieces，andlackstheknowledgebasethatcouldmeettherequirementsofrationaluseofTCMdecoctionpieces.Therefore，itisnecessarytoconstructasetofknowledgebasewhichcanmeettheevaluationrequirementsof“consistencyofprinciple，methodandprescriptionuse”ofTCMdecoctionpiecesundertheguidanceofTCMtheoreticalsystem.Itscontentsincludethatpatientinformationcollection，constructionofknowledgebaserelatedtodiseasesandsyndromes，selectionofprocessedproductsofTCMdecoctionpieces，additionandsubtractionofclinicalsymptoms，selectiontabooofvarietiesofTCMdecoctionpieces，...