Coldmedicine:newswar,PRbattle?NewContaccoldmedicinesuchasacetaminophenexceededtheincidentbecamehotnews,but,thisnewsisawell-plannedwarpharmaceuticalbusinesswar,directedattheUnitedStatesGlaxoSmithKline,Bristol-MyersSquibbandothergiantscompetingproducts.CouldlaunchthisBattlealsoDengxianzhibei.FDAnoticesoftheletterisactuallyoldnews.2011January13,FDApublishedaboutloweringprescriptiondrugacetaminophenliverdamageriskmeasures,includingrestrictionsonacetaminophenprescriptionspecifications,eachpiece/particlecontentisnotmorethan325mg,whileincreasingtheriskofliverdamageandallergicreactionswarninginthepackageinsert.Excessiveuseofacetaminophen,orwhileusingmorethanoneacetaminophen-containingproducts,ordrinkingalcoholwhilethecase.Severeliverdamagecanleadtoliverfailure,livertransplantation,anddeathIn1998to2003,acetaminopheninducedacuteliverfailurefortheUnitedStatesmostdrugs,thereare131casesin275cases(48%ofaccidentaloverdosecaused.2007U.S.CDCdata,the1nation’s1,600casesofacuteliverfailurecasesannually,acetaminophenisthemajorcauseofliverfailure.FDAsurethateverypieceofnotmorethan325mgofacetaminophencompoundonthetreatmentofpainisstillvalid,doesnotaffectexistingDosagesuchpreparations.Patientsstillundertheguidanceofadoctortaking1-2tabletsmedicationeverydaynomorethan6times,anddonotexceedthemaximumdailydoseof4000mgofthedrugmanufacturerswillhavethreeyearstochangethespecificationsofprescriptiondrugs,prescriptiondrugsmanualisbeingrevised,addingaboutsevereliverdamageboxedwarning.OTCdrugs(suchasTylenolunaffected,suchinformationhasbeenincludedinthespecification.Difficulttoseethefullannouncementfromtheabove,thisisjustanormalroutinedocuments.Donothaveahighdegreeofpanic.FDAdidnotreducetheuseofsuchformulationsdaydose,butreducethedosepertablet,patientscanstilluse1-2tabletseverynotonlyallowstheuseofadaily325mg.medicationfromtheperspectiveofscience,itdoesnotsaythatonaper-use500mg325mgtwopairsofliverinjuryismoreseriousthantheuse,butshouldbejusttheopposite.2kindofdrug-inducedliverinjurylong-termaccumulationofexcessiveuseormisuseoftheresultsduetotheoccasionalcoldwithoutusinghightension,anxietyandexcessive.clinicalresponsetoacetaminophen-inducedliverinjuryisthemosteffectivetreatmentfordrugacetylcysteine​​injection,arelistedintotheUnitedStatestreatmentguidelines,theEUandChinatreatmentguidelinesthreeguidetreatmentguidelines.FDAwordingindirectreferencetoaspecificbrandreallyintriguingcontrastwiththeoriginalFDAnewsreleaseiseasytoseewhereNiend.NewContacbluedressitselfdoesnotcontainacetaminophencomponent,althoughitcontainsareddress,butareinlinewithnationalpharmaceuticalstandards.hundredNingsparedothercompetingproducts,allshotintheinternationalgiants,butalsoneedthespiritoffaircompetition,thespiritandprinciplesofscience-based,towintherespectandcredibilityinthebattletobattle,ratherthanbycausingpublicpanic,suppressopponentstowinoneo’clocksales.Thisisthefragmentednatureofthecompetitorsjoinforcestofightbackif,itsunfaircompetitioncounterclaim,orchestratedacenturytowarwouldbe3counterproductive,lostreputation.Similarbusinesswarisnotuncommon,asearlyasinthepreviousHONZpediatricNimesulideeventisavividscene.Essenceofmarketing,therealoperation,wemuststriveforexcellence,professionalismcorrect,completehardwareandsoftware,andcanwithstandthemostrigorousquestioninganddemandingscrutinyThereisatraceofvulnerabilitywillbetheopp...