[摘要]目的探讨微创颅内血肿清除术联合丹参注射液治疗高血压脑出血的临床疗效。方法选取本院收治的高血压脑出血患者98例,并随机分为两组,观察组49例给予微创颅内血肿清除术并同时加丹参注射液10~20mL治疗,对照组49例应用小骨窗颅内血肿清除术治疗,比较两组的临床效果。结果观察组总有效率为880%,对照组为751%,两组比较差异有统计学意义(P<0.05),观察组的手术时间、术中平均出血量、再出血率、住院时间及GCS评分明显优于对照组(P<0.05)。结论微创颅内血肿清除术联合丹参注射液治疗高血压脑出血,能有效地降低再出血率,并发症少,生存率高,有利于神经功能恢复及提高患者的生活质量。[关键词]高血压脑出血;微创颅内血肿清除术;小骨窗颅内血肿清除术;丹参注射液[]R7215+1[文献标识码]A[]1674-4721(20XX)04(a)-0048-03ObservationofthecurativeeffectontheminimalremovedofintracranialhematomacombinedwithDanshenrootinjectiontreatmentforthehypertensiveintracerebralhemorrhageLINKuanCHENGJunchangLIUHaishengNeurosurgeryDepartment,ChenxinghaiHospitalofZhongshanCityinGuangdongProvince,Zhongshan528415,China[Abstract]ObjectiveToinvestigatetheclinicaleffectoftheminimalremovedofintracranialhematomacombinedwithDanshenrootinjectiontreatmentforthehypertensiveintracerebralhemorrhage.Metho党史Ninety-eightpatientswithhypertensiveintracerebralhemorrhagewerechosenfromourhospital,andrandomlydividedintotwogroups,49casesintheobservationgroupweretreatedbytheminimalremovedofintracranialhematoma,andthenaddedtheDanshenrootinjectionfor10-20mL,and69casesinthecontrolgroupweretreatedbythesmallbonewindowevacuationofintracranialhematoma,andcomparedtheircurativeeffects.ResultsThetotaleffectiverateoftheobservationgroupwas880%,thecontrolgroupwas751%,thereweredifferentstatisticalsignificancebetweenthem(P<0.05),theoperationtime,theaverageamountofthebleedingginintra-operative,hemorrhagedrateagain,lengthofstayandGCSintheobservationgroupwereallmoreexcellentthanthecontrolgroup,thereweredifferentstatisticalsignificancebetweenthem(P<0.05).ConclusionTheminimalremovedofintracranialhematomacombinedwithDanshenrootinjectiontreatthehypertensiveintracerebralhemorrhage,itcanlowthehemorrhagedrate,lesscomplication,survivalrateishigh,itisgoodforrenewingthecranialnervefunctionandimprovingthepatient"squalityoflife.[Keywor党史]Hypertensiveintracerebralhemorrhage;Minimalremovedofintracranialhematoma;Smallbonewindowevacuationofintracranialhematoma;Danshenrootinjection高血压脑出血(hypertensiveintracerebralhemorrhage,HICH)是由脑内动脉、静脉或毛细血管破裂引起脑实质内的一种自发性脑出血病,是目前严重威胁人类健康的一类常见的神经内科脑血管疾病,其具有发病突然,病情凶险,进展迅速,死亡率及致残率高的特点[1]。早期病死率高达44%,脑深部出血死残率更高[2]。该病的预后很差,严重影响着患者的生活质量。在治疗上一般采用手术治疗,传统的方法是行开颅血肿清除术,这种方法对于患者的创伤大,导致预后不佳。随着医学技术的发展,微创血肿清除引流手术是近年来治疗HICH较为简便有效的方法,其治疗急性脑血管病的疗效已被国内外所公认[3]。目的是采用适当的术式,及时清除血肿缓解或解除脑受压,同时避免任何不必要的脑损伤与由此造成或加重的伤残,达到在挽救生命的同时,降低伤残率和提高生存质量。笔者采用微创颅内血肿清除术联合丹参注射液治疗HICH,疗效较好,现总结分析报道如下1资料与方法1一般资料选择20XX年1月~20XX年10月本院住院的HICH患者98例,诊断均符合1995年全国第四届脑血管病学术会议通过的《各类脑血管疾病的诊断要点》[4],其中,男62例,女36例,年龄36~75岁,平均(65±7)岁,高血压病史1~20年,平均(8±5)年。发病至手术时间6h~6...