[经典]高血压患者糖代谢状态及其相关因素探论高血压患者糖代谢状态及其相关因素探论[摘要]目的:探讨高血压患者糖代谢状态及其相关因索。方法:167例高血压患者晚餐后禁食12〜14h,次日清晨抽血,分别测定血糖、TC、TG、HDL-C和LDL-C,并完成血压、体脂参数等测定。结果:本研究中高血压患者糖代谢异常的发生率高达68.3%o在对高血压患者不同糖代谢状态所占数目及其构成比的研究中,DM组、IFG组和IGT组的男女数耳经统计,P<0.05,差异有统计学意义,不同年龄段高血压患者糖代谢异常组例数的分布情况看,46〜55岁和56〜65岁两个年龄段的数目比例较高;Logistic冋归分析显示年龄、性别、饮酒、肥胖、T2DM家族史、高血压病程、BMI、血脂与高血压患者糖代谢异常的发生独立正相关。结论:高血压患者合并糖代谢异常较常见;男性患者更易发生糖代谢异常;性别、年龄、饮酒、原发性高血压病(EH)家族史、T2DM家族史、EH病程长、高收缩压、高血脂是糖耐量正常EH患者发生糖代谢异常的独立危险因索。一旦怀疑,应积极干预,及时进行危险因素评估。[关键词]原发性高血压;糖代谢异常;相关因素[中图分类号]R544.1[文献标识码]A[文章编号]1674-4721(2010)04(a)-029-03StatusofglucosemetabolisminpatientswithhypertensionanditsrelatedfactorsonexplorationLIAOXuequan,HUCaizhen,HUANGZengxiang(WanjiangHospitalofDongguanCity,Dongguan523050,China)[Abstract]Objective:Toinvestigatethestatusofglucosemetabolisminpatientswithhypertensionanditsrelatedfactors・Methods:167patientswithhypertensionafterdinnetfasted12-14h,thenextmorningabloodsample,bloodglucoseweremeasured,TC,TG,HDL-CandLDL-C.Andcompletebloodpressure,bodyfatparametersmeasured・Results:Inthisstudy,abnormalglucosemetabolisminpatientswithhypertensionincidencerateof68.3%.Inhypertensivepatientswithdifferentstatusofglucosemetabolisminthenumberandcompositionratioofshareofthestudy,DMgroup,IFGgroupandIGTgroupthenumberofmenandwomenthroughthestatistics,P<0.05,withasignificantdifference;glucoseinhypertensivepatientsofdifferentagesmetabolicdisordersgroupdistributionofthenumberofcasesofview,46-55and56-65yearsoldgroupthenumberoftwohighproportion;Logisticregressionanalysisshowedthatage,sex,drinking,obesity,T2DMfamilyhistory,hypertensionduration,BMI,bloodlipidsandhypertensionincidenceinpatientswithabnormalglucosemetabolismindependentpositivecorrelation.Conclusion:Theabnormalglucosemetabolisminpatientswithhypertensionmorecommon;malepatientsmorelikelytohaveabnormalglucosemetabolism;sex,age,alcoholconsumption,Elifamilyhistory,T2DMfamilyhistory,EHlongerduration,highsystolicbloodpressure,highcholesterolisanormalglucosetoleraneeElioccurredinpatientswithabnormalglucosemetabolismindependentriskfactors・Oncethesuspectshouldactivelyintervenetimelyassessmentofriskfactors・[Keywords]Hypertension;Abnormalglucosemetabolism;Relatedfactors近年来,随着人们生活习惯和饮食结构的改变,糖代谢障碍[糖尿病、空腹血糖升高(IFG)、糖耐量低减(IGT)]的发病率明显增加,当这些疾病与高血压合并出现吋,心血管病发生率明显高于单纯高血压疾病,可达3倍Z多,且以男性居多。为了更好地降低高血压并发症,提高患者的&活质量,有必要对该病的糖代谢障碍影响及相关因素进行探讨。为此本院对2008年1月〜2009年6月就诊于本院内科门诊的167例鮎血压患者的临床资料进行统计分析,现将结果公布如下:1资料与方法1.1一般资料2008年1月〜2009年6月就诊于本院内科门诊的167例高血压患者,男108例,女59例,男女之比为1.8:1,年龄35~63岁,平均(43.4±10.5)岁。其中血压测量采用经BHS(britishhypertensionsociety)标准认证[1]、经水银血压计校验的“松下(Panasonic)EW3005"电了血压计,坐位测左上肢血压,连续测量3次,间隔1min,取3次均值作为个体血压值...