+6GzandnoisemultiplestressonlearningandmemoryfunctionAuthor:Xi-QingSun,TingLiuSong,FORCES,Xing-YuWu[Keywords]noise[Abstract]AIM:Tostudytheeffectsofcombinedstressofnoiseandmoderate+Gzonlearningandmemoryinrats.METHODS:ThirtytwomaleSDratswererandomlydividedintofourgroupswith8ratsineachgroup:controlgroup,+6Gz/3mingroup,90dB(A)/30minnoisegroup,+6Gz/3minand90dB(A)/30minnoisecombinedstressgroupandthechangesoflearningandmemoryafterstressweremeasuredbyYmazetestandstepthroughtest.RESULTS:Ascomparedwiththatincontrolgroup,thepercentageofrightreactiondecreasedsignificantly(P0.01)andthereactiontimeincreasedsignificantly(P0.01)in+Gzgroupat2d,4dand6dafter+Gzexposure.Whencomparedwiththatincontrolandnoisegroup,thepercentageofrightreactiondecreasedsignificantly(P0.01)andthereactiontimeincreasedsignificantly(P0.01)atalltimepointsincombinedstressgroup,butnosignificant---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---changeswereobservedwhencomparedwiththatin+Gzgroup.Ascomparedwiththatincontrolgroup,thetotaltimeandnumberoferrorincreasedsignificantly(P0.01)whilelatenttimedecreasedsignificantlyimmediatelyand6daysafterstress(P0.05)incombinedstressgroup.CONCLUSION:Itissuggestedthatcombinedstressof+6Gz/30minand90dB(A)/30minnoisemaycausesustainedimpairmentoflearningandmemoryinrats.[Keywords]stress;+Gz;noise;learningandmemory;rats[Abstract]Objective:Toinvestigatethemoderate-intensitypositiveaccelerationandnoiseimpactofmultiplestressonlearningandmemoryfunctioninratsMethods:MaleSDratswererandomlydividedintocontrolgroup,+6Gz/3mingroup,90dB(A)/30minnoisegroup,+6Gz/3minand90dB(A)/30minnoisecompositestressgroupfourgroups,eachofeightY-mazetestandpassiveavoidancetestobservedstressatdifferentchangesinthefunctionoflearningandmemoryinratsresults:+Gzgroupratscorrectrateafterexposureto2,4and6dcomparedwiththecontrolgroupweresignificantlylower(P《0.01),thereaction---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---timewassignificantlyextended(P《0.01).compositethestressedratscorrectrateafterexposureateachtimepointcomparedwiththecontrolgroupandnoisegroupweresignificantlylower(P《0.01),thereactiontimeweresignificantlylonger(P《0.01),comparedwith+Gzgroupiftherewasnosignificantchangetotaltimeanderrornumberafterexposureinstantlycomparedwiththecontrolgroupsignificantlyincreased(P《0.01),theincubationperiodafterexposureinstantlynoticeablewithshortening(P《0.05)exposed6dafterremainedsignificantlyshorter(P《0.05).conclusions:+6Gz/3minand90dB(A)/30minnoisecompositestresscancausetheratpersistentlearningandmemorydysfunction.[Keywords]stress,positiveacceleration,noise,learningandmemoryinrats0IntroductionSpecialmilitaryflightworkenvironment,inevitablyexposedtovariousstressors,includingtwoofthemorecommonaviationstressorspositiveacceleration(+Gz)andnoisethreattoflightsafetyhasbecomeanimportantfactorinthefighterpilot.Therefore,theeffectandmechanismofmultiplestresseffectsontheabilityoftheflightcrewhas---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---importantpracticalsignificancetoourpreviousstudies,highG(+10Gz/3minand90dB(A)/30minnoisecompositeshouldavoidover-stimulatedcancausetheratpersistentlearningandmemorydysfunction,whichthehigh-Gasthemaininfluencingfactors[1]However,intheactualflight,thefighterpilotsthroughtheirownmaneuversandaircraftattitudeadjustment,canbepartlyunde...