HIV/AIDS病人抗病毒治疗6月后住院原因分析吴念宁，彭智鹏黄绍标(南宁市第四人民页院广西艾滋病临床治疗屮心，南宁530023)摘要：目的了解广西地区艾滋病病毒(HIV)感染者/艾滋病(AIDS)病人(简称HIV/AIDS病人)经高效联合抗反转录病毒治疗(HAART)超过6个月后所患疾病谱及对预后彩响。方法回顾性分析2010年4月至2015年3月HAART超过6个月后HIV/AIDS病人住院的主要原因，将所患疾病分类为：HAART药物不良反应、急性感染性疚病、传染性肝病、结核病、其他传染病、内科系统疾病、外科系统疾病、外伤、肿瘤、其他疾病共10类，观察各类疾病的发生情况及对预后影响。结果共收集符合条件病人818例，男性占71」％,年龄＞50岁占47.1%,CD4-T淋巴细胞计数＜200^/PL者占32.5%。各类疾病屮，急性感染性疾病占19.6%,内科系统性疾病占17%,外科系统性疾病占13.9%,肿瘤占12.6%,HAART药物不良反应占&3%,结核病占8.9%,传染性肝病占5.7%,其她传染病占5%,外伤占3.7%,其他疾病占5.4%。不良预后病人占10.9%,其中前三位为恶性肿瘤(47.2%)、急性感染(25.8%)和慢性肝病(9.0%)。结论本地区HIV/AIDS病人基础免疫低下多见，中长期HAART过程屮感染性疾病风险较大，老年人比例高，合并病种多样，恶性肿瘤和感染是不良预后的主要原因。关键词：艾滋病病毒：高效联合抗反转录病毒治疗；住院原因;疾病谱中图分类号：R373.9：R512.91文献标志码：A文章编号：1672・5662(2016)05-0000-00AnalysisonhospitalizationcausesofHIV/AIDSpatientsaftersix-month'sHAARTWuNianning■PengZhipeng,HuangShaobiao.(TheFourthPeoplesHospitalofNanningHIV/AIDSClinicalTreatmentCenterinGuangxi-Nanning,530023,Guangxi,China)SupportedbytheNationalKeyS&TSpecialProjects(2012ZX10004910-006)andbyScientificResearchandTechnologyDevelopmentprogramofNanning(201109047C)AbstractObjectiveToinvestigatethediseasespectrumandinflueneeonprognosisofHIV/AIDSpatientsunderhighlyactiveantiretroviraltherapy(HAART)oversixmonthsinGuangxi.MethodsAretrospectiveanalysiswasmadeforthehospitalizationcausesofHIV/AIDSpatientsunderHAARToversixmonthsduringApril2010toMarch2015.TheincidenceofthediseaseswasobservedincludingsideeftectsofHAARXacuteinfectiousdiseases,infectioushepatitis,tuberculosis,otherinfectiousdiseases,internalsystemdiseases,surgicalsystemdiseases,trauma,cancersandmiscellaneous,andtheinfluenceontheprognosiswasanalyzed・ResultsAtotalof818conditionedcaseswerecollectedwith71.1%ofmales,47.1%overtheageof50years,and32.5%whoseCD4T-lymphocytecountbelow200copies/pL.Amongthevariousdiseasesdescribedabove,acuteiniectiousdiseasesaccountedlor19.6%,internalsystemicdiseaseslor17%,surgicalsystemdiseasesfor13.9%,cancersibr12.6%,HAARTsideeffectsfor8.3%,tuberculosisfor8.9%,iniectioushepatitislor5.7%,otherinfectiousdiseasesfor5%,traumalor3.7%,andotherdiseasesfor5.4%・Patientsofpoorprognosisaccountedfor10.9%・Amongthemthetopthreewerecancers(47.2%),acuteinfections(25.8%),andchronicliverdiseases(9%).ConclusionHIV/AIDSpatientsinGuangxiaremostlyimmunocompromised.TherisksofopportunisticinfectionsarestillhighinthemediumandlongtermprocessofHAART.Ahighproportionhasbeenseeninagedpatientswithdiversityofcomplicationsanddiseases.Themaincausesofpoorprognosisremaincancersandinlections.Keywords:HIV;HAART;HospitalizationCauses;Diseasespectmm收稿日期：2015-11-13：修回日期：2016-02-16基金项目国家重大科技专项项目课题(2012ZX10004910-006)：南宁市科学研究与技术开发汁划项H(2011090470作者简介：吴念宁(1962-),男，广西壮族自治区天峨县人，主任医•师，主要从事艾滋病临床诊疗。Email：wunianning62@163.com高效联合抗反转录病毒治疗(Highlyactiveantiretroviraltherapy,HAART)仍是li前被证实的针对艾滋病病毒（Humanimmunodeficiencyvi...