MRI对原发性中枢神经系统淋巴瘤的诊断价值探讨刘海平胡海菁莫森林【摘要】目的探讨磁共振成像（MRI）对原发性中枢神经系统淋巴瘤（PCNSL）的诊断价值。方法50例疑似原发性中枢神经系统淋巴瘤患者，随机分为对照组与研究组，各25例。对照组患者接受CT检查，研究组患者接受MRI检查。分析所有患者的手术病理结果;对比两组患者对病灶的检测准确率。结果50例患者均接受手术病理确诊，对照组患者中有64个病灶，边界清晰的38個，边界较为清晰的19个，边界模糊不清的7个;所有病灶均未出现出血以及钙化，仅有18个病灶周围未见水肿;研究组患者中有73个病灶，边界清晰的43个，边界较为清晰的21个，边界模糊不清的9个;所有病灶均未出现出血以及钙化，仅有20个病灶周围未见水肿。研究组患者的病灶、边界清晰、边界较为清晰、病灶周围未见水肿的检测准确率分别为95.89%、95.35%、95.24%、95.00%，均高于对照组的73.44%、78.95%、63.16%、55.56%，差异有统计学意义（P0.05）。结论原发性中枢神经系统淋巴瘤采用进行MRI诊断，结合患者的个体情况，可对于确诊原发性中枢神经系统淋巴瘤有一定的提示作用，同时MRI还能探查到患者的病灶具体情况，为患者临床治疗方案提供参考依据，该诊断方式值得推广。【关键词】原发性中枢神经系统淋巴瘤;磁共振成像;CTDOI：10.14163/jki.11-5547/r.2020.07.010DiscussionondiagnosticvalueofMRIinprimarycentralnervoussystemlymphomaLIUHai-ping，HUHai-激ng，MOSen-lin，etal.FoshanNanhaiDistrictPeoplesHospital，Foshan528200，China【Abstract】ObjectiveTodiscusstheclinicalvalueofmagneticresonanceimaging（MRI）indiagnosisofprimarycentralnervoussystemlymphoma（PCNSL）.MethodsAtotalof50casesofsuspectedprimarycentralnervoussystemlymphomawererandomlydividedintocontrolgroupandresearchgroup，with25casesineachgroup.ThecontrolgroupreceivedCTexamination，andtheresearchgroupreceivedMRIexamination.Thesurgicalandpathologicalresultsofallpatientswereanalyzed，andtheaccuracyrateoflesionsdetectionbetweenthetwogroupswascompared.ResultsAll50patientswerediagnosedbysurgeryandpathology.Therewere64lesionsinthecontrolgroup，ofwhich38lesionswithveryclearboundary，19lesionswithclearboundary，and7lesionswithambiguousboundary.Nobleedingorcalcificationwasfoundinalllesions，only18lesionswithnoedemaaround.Therewere73lesionsinthecontrolgroup，ofwhich43lesionswithveryclearboundary，21lesionswithclearboundary，and9lesionswithambiguousboundary.Nobleedingorcalcificationwasfoundinalllesions，only20lesionswithnoedemaaround.Thedetectionaccuracyoflesions，veryclearborder，clearborderandlesionswithnoedemaaroundintheresearchgroupwere95.89%，95.35%，95.24%and95.00%respectively，whichwerehigherthan73.44%，78.95%，63.16%and55.56%，respectivelyinthecontrolgroup，andthedifferencewasstatisticallysignificant（P0.05）.ConclusionTheapplicationofMRIindiagnosisofprimarycentralnervoussystemlymphoma，combinedwiththeindividualsituationofthepatient，cangivesomehintsforthediagnosisofprimarycentralnervoussystemlymphoma.Atthesametime，MRIcandetectthespecificsituationofthepatient'slesionsandprovidereferencefortheclinicaltreatmentplanofthepatient.Thisdiagnosismethodisworthpopularizing.【Keywords】Primarycentralnervoussystemlymphoma;Magneticresonanceimaging;CT原发性中枢神经系统淋巴瘤（primarycentralnervoussystemlymphoma，PCNSL）指的是淋巴瘤发生于患者的中枢神经系统，且未受累其他部位，原发性中枢神经系统淋巴瘤在颅内肿瘤发生率中占据1%～2%，该疾病为一种极少见的非霍奇金淋巴瘤，恶性程度较高，患者的预后效果较差，有统计学资料表明，携带艾滋病（HIV）病毒人群发生原发性中枢神经系统淋巴瘤的几率远高于正常人群，目前对于原发性中枢神经系统淋巴...