输尿管软镜联合钬激光治疗上尿路结石的临床研究［摘要］H的探讨输尿管软镜联合钬激光治疗上尿路结石的存效性与安全性。方法选取2014年1月〜2016年1月收治的上尿路结石患者200例作为研究对象，按照数字表法随机分为两组，对照组采用经皮肾镜穿刺取石术；观察组患者采用输尿管软镜联合钬激光术；观察两组结石患者的手术时间、术中出血景、术后疼痛、下床活动时间、住院时间、结石清除率及不良反应发生情况。结果观察组患者手术时间、术中出血量等均明显低于？*兆椋?而结石清除率明显高于对照组，且差异均有统计学意义（P<0.05）；观察组患者下床活动时间、住院时间等均明显少于对照组，而术后疼痛率明显低于对照组，且差异均有统计学意义（P〈0.05）;观察组患者不良反应发生率为14.0%,对照组不良反应发生率为24.0%，两组不良反应发生率比较差异有统计学意义（P〈0.05）。结论对上尿路结石患者行输尿管软镜下钬激光碎石术，配合术中良好的操作技巧，可以提高肾下盏结石清除率，降低不良反应发生率。本文采集自网络，本站发布的论文均是优质论文，供学习和研究使用，文中立场与本网站无关，版权和著作权归原作者所右，如存不愿意被转载的情况，请通知我们删除己转载的信息，如果需要分享，请保留本段说明。［关键词］电子输尿管软镜；上尿路；结石；钬激光［中图分类号］R699［文献标识码］A［文章编号］2095-0616(2017)10-156-04ClinicalstudyonflexibleureteroscopecombinedwithholmiumlaserintreatmentofupperurinarycalculiWUZhaochunHANQiaojunXUHanxinQIUJinxinDepartmentofUrinarySurgery,DongguanQingxiHospital,Guangdong523660，China［Abstract］ObjectiveToexploretheeffectivenessandsafetyofflexibleureteroscopecombinedwithholmiumlaserintreatmentofupperurinarycalculi.Methods200patientswithupperurinarycalculiwhowereadmittedfromJanuary2014toJanuary2016wereselectedasresearchobjectsandtheywererandomlydividedintotwogroupsaccordingtothedigitaltablemethod.Thecontrolgroupwastreatedwithpercutaneousnephrolithotomy.Patientsintheobservationgroupwasgivenflexibleureteroscopecombinedwithholmiumlaser.Operativetime,intraoperativebloodloss,postoperativepain,outofbedactivitytime,hospitalstay,stoneclearancerateandadversereactionsofpatientsintwogroupswereobserved.ResultsOperativetimeandintraoperativebloodlossofpatientsintheobservationgroupwerebothsignificantlylowerthanthoseofthecontrolgroupwhilethestoneclearanceratewassignificantlyhigherthanthatofthecontrolgroup.Comparativedifferenceshadstatisticaldifference（P〈0.05）.Outofbedactivitytimeandhospitalstayofpatientsintheobservationgroupwerebothsignificantlyshorterthanthoseofthecontrolgroupwhilerateofpostoperativepainwassignificantlylowerthanthatofthecontrolgroup.Comparativedifferenceshadstatisticaldifference（P〈0.05）.Theincidenceofadversereactionsoftheobservationgroupandthecontrolgroupwas14.0%and24.0%respectively.Comparativedifferenceinincidenceofadversereactionsbetweentwogroupshadstatisticalsignificance（P<0.05）.ConclusionForpatientswithupperurinarycalculi,holmiumlaserlithotripsyunderflexibleureteroscopecombinedwithgoodintraoperativetechniquecanimprovetheclearancerateofsubrenalcalyxcalculusandreducetheincidenceofadversereactions.[Keywords]Electronflexibleurctcroscopc；Upperurinarytract；Stone；Holmiumlaser肾和输尿管结石是泌尿科最常见的疾病，主要临床症状为腰部出现不同程度的酸胀、绞痛等[1]。常规的手术治疗措施有体外冲击波碎石术、输尿管硬镜、经皮肾镜穿刺取石术，其中体外冲击波碎石术具有风险小、操作简便等特点，适合于基层医院应用，经皮肾镜穿刺取石术结石清除率高［2-3］。但是，常规手术治疗方法均伴有不同程度的肾功能损伤、输尿管损伤、感染及出血等，加重患者的病情［4］...