肾脏嗜酸细胞腺瘤的螺旋CT诊断与病理对照分析【摘要】目的:分析肾嗜酸细胞瘤的多排螺旋CT增强扫描特征及病理表现,以提高诊断准确性。方法:对12例经手术后病理证实的肾嗜酸细胞腺瘤患者的多期增强CT影像学特点及病理结果进行回顾性分析。结果:11例为单发病灶,1例为多发病灶。病灶最大径20.0〜87.0mm,平均53.5mmo1例行CT平扫显示肿瘤实质呈略高密度影,中心瘢痕呈低密度影。皮质期5例不均匀强化,6例肿瘤实性部分较均匀强化,所有病灶强化程度均高于髓质,低于皮质;实质期病灶强化程度均低于髓质,2例欠均匀强化,10例病灶密度趋向均匀强化;延迟期肿瘤实性部分整体密度较均匀强化并低于肾实质,与病理上该肿瘤较少发生出血、坏死、囊变相对应。其中1例双肾多灶病变亦遵循上述强化方式。6例见中央裂隙状或星芒状瘢痕,所有病例均未见钙化。结论:肾嗜酸细胞瘤是一种少见的肾脏良性肿瘤,多期螺旋CT增强扫描有一定影像学特点,如果能在术前提示到本病的可能性,可采取肾穿刺活检或手术中冰冻病理活检,对临床手术治疗方案的制定有重要参考意义。【关键词】肾嗜酸细胞腺瘤;诊断;螺旋CT;病理TheComprehensiveDiagnosisofRenalOncocytomabySpiralCTandPatho1ogy/ZHANGQing,LIJun~tang,ZHANGJin-feng,etal.//MedicalInnovationofChina,2015,12(10):124-129[Abstract]Objective:ToanalyzetheproblemsindiagnosingrenaloncocytomabyspiralCTandpathology,inordertoimprovetheaccuracyofdiagnosis.Method:TheimagingfeaturesofCTof12lesionsconfirmedbypathologywereanalysedretrospectivelyandcorrelatedbypathologicdiagnosis.ResuIt:11casesweresinglenodule,accompanyingwiththediameteroflesionwas20-87.0mm,average53.5mm.ONplainCTsean,1lesionshowedalittlehigherdensitythantherenalparenchyma*centralstellatescarshowedlowdensityshadow・Inthecorticalphase,5casesdisplayedinhomogeneousenhancement,and6casesdisplayedhomogeneousenhancementinpart.Theenhanceddegreeofalllesionswerehigherthanthatofmedulla,andlowerthanthatofcortex.Inparenchymalphase,theenhanceddegreeofalllesionswerelowerthanthatofmedulla・Inexcretoryphase,thedensityofsolidpartoftumorwasequation,andbelowthatoftherenalparenchyma,whichwascorrespondingwiththepathologicalfeature:thetumorwaslessofhemorrhage,necrosisandcysticdegeneration.Thecaseofbilateralmultiplerenallesionsalsofollowedthestrengtheningmethod.6casesshowedcentralslitshapedorstellateshapedscar,andallcasesshowednocalcification.Conclusion:Sincerenaloncocytomaisakindofbenignrenaltumor,whichhassomeimagingfeaturesinenhancedspiralCTsean,takingrenalbiopsybeforeoperationorsurgeryfrozenbiopsywillbeusefultomaketherapyplanforthebenefitsofpatients.[Keywords]Renaloncocytoma;Diagnosis;SpiralCT;PathologyFirst-author?saddress:QingdaoMunicipalHospital,Qingdao266071,Chinadoi:10.3969/j.issn.1674-4985.2015.10.041肾嗜酸细胞腺瘤(Renaloncocytoma,RO)是一种少见的肾脏良性上皮性肿瘤,无特异性临床表现,多为偶然发现,近些年发生率有所增高,可能与临床对本病认识增加与病理免疫组化的进展,以及人们健康意识增强并健康查体有关,由于与肾癌难以鉴别,临床经常行肾癌根治术,而术后病理诊断为本病。本文回顾性分析经病理证实的12例肾嗜酸细胞腺瘤的CT表现,旨在提高对本病的影像学认识,为临床术前正确诊断提供参考。1资料与方法1.1一般资料2007年9月-2014年5月经手术病理证实的12肾嗜酸细胞腺瘤患者,男6例,女6例,年龄44~76岁,平均年龄60岁;体检发现9例,因腰部不适或疼痛、腹痛就诊3例;9例行根治性肾切除术,3例行肾部分切除术;1例为多灶性,11例为单发。1.2方法使用SIEMENS公司的SOMATOMSensation64螺旋CT扫描机,扫描参数管电压120kV,管电流250mA,层厚1.5mm,螺距0.8。增强对比剂使用GE公司的碘海醇,浓度300mgl/mL,用量80-100ml,注射速率3.0-4.0mL/so增强三...