不孕患者体外受精胞浆内单精子注射妊娠结局的回顾性分析游焱球1邓小云2温丽萍1(1广东省韶关市妇幼保健院生殖科512026)(2韶关市粤北人民医院广东韶关512026)【摘要】目的探讨不孕患者应用体外受精/胞浆内单精子注射(IVF/ICSI)妊娠结局的回顾特点。方法本次选取100例接受IVF/ICSI助孕的不孕患者作研究对象，分析影响妊娠结局的因素。结果本次选择的100例不孕患者，年龄&le;30岁50例，31-35岁40例，&ge;36岁10例。妊娠率分别为56%,47.5%,40%。总妊娠率为51%。显示随年龄堉加，妊娠率呈下降趋势，年龄&le;30岁妊娠率明显高于其它两组(P<0.05)。继发不孕54例，原发不孕46例，前者妊娠率为51.8%,50%,组间比较无明显差异(P&gt；0.05)o卵巢功能低下占1%，排卵巢障碍占5%,输卵管因素占85%,其它因素占9%。非条件logistic回归分析显示，针对妊娠结局，HCG口P值，用药方案，BMI为危险因素(&beta;>0,OR>l),而内膜厚度、即往妊娠史、总优胚数、M2卵泡数为保护因素(&beta;<0,OR<l)。超排方案中，短方案组10例，长方案组90例，妊娠率分别为30%,70%,差异有统计学意义(P<0.05)o结论影响IVF/ICSI妊娠结局的因素较多，针对不孕接受IVF/ICSI助孕治疗的患者，获得成功妊娠为多因素共同作用结果，需建立个体化治疗方案，防范不良因素，以提高妊娠成功率，满足不孕患者的生育需求。【关键词】不孕体外受精胞浆内单精子注射妊娠结局回顾【中图分类号】R3【文献标识码】A【文章编号】2095-1752(2014)07-0019-02AretrospectiveanalysisoftheinfertilepatientsIVF/intracytoplasmicsperminjectionpregnancyoutcome【Abstract】Objective:ToinvestigatethecharacteristicsofsperminjectionReview(IVF/ICSI)intheinfertilepatientswithIVF/---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---ICSIpregnancyoutcome.Methods:The100patientstoreceiveIVF/ICSIprogesteroneinfertilitypatientsforthestudy,analysisoffactorsaffectingtheoutcomeofpregnancy.Result:Theselected100casesofinfertilitypatients,aged&le;30yearsold50cases40cases,31-35years,&ge;36yearsofagein10cases.Pregnancyrateswere56%,47.5%,40%.Thetotalpregnancyratewas51%.Showwithincreasingage,pregnancydeclined,age&le;30yearsofagepregnancyratewassignificantlyhigherthantheothertwogroups(P<0.05).Secondaryinfertilityin54cases,46casesofprimaryinfertility,pregnancyformer51.8%,50%,nosignificantdifference(P>0.05)betweenthetwogroups.1%ofovariandysfunction,rankedovariandisordersaccountedfor5%,85%tubalfactor,otherfactorsaccountedfor9%.Unconditionallogisticregressionanalysisshowedthatforthepregnancyoutcome,HCGDayPvaluesregimen,BMIisariskfactor(&beta;>0,OR>1),andendometrialthickness,thatis,topregnancyhistory,thetotalnumberofqualityembryo,M2folliclesnumberofprotectivefactors(&beta;<0,OR<l).Superovulationscheme,theshortprogramgroup10cases,90casesoflongprotocolgroup,thepregnancyratewas30%,70%,thedifferencewasstatisticallysignificant(P<0.05).Conclusion:ThefactorsaffectingIVF/ICSIpregnancyoutcomemore,IVF/ICSItreatmentforinfertilitypatientstoreceiveprogesterone,tobesuccessfulpregnancyistheresultofmanyfactors,theneedtoestablishindividualizedtreatmentprogramstopreventadversefactors,inordertoimprovepregnancysuccessrate,tomeettheneedsoffertilityinfertilitypatients.【Keywords】infertilityIVFcytoplasmicsperminjectionpregnancyoutcomesReview人类辅助生殖技术(ART)在相关国际监督委员会的定义为采用人工技术/方法对人类精子和卵母细胞操作，达到获得新生命的S的［1,2】。胞浆内单精子注射(ICSI)和人类体外受精-胚胎移植(IVF-ET)研究已取得显著成就，英国---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---剑桥在上世纪70年代末诞生了世界第一例试管婴儿，在医学史上具开拓性意义[3】。0前此项技术...