早孕前后子宫动脉血流变化与妊娠结局的相关研究1山东省潍坊市人民医院产二科山东潍坊261041;2.山东省潍坊市人民医院习惯性流产科山东潍坊261041［摘要］目的：通过对育龄期正常及复发性流产(RecurrentSpontaneousAbortion,RSA)妇女备孕前1个月及孕后10周内子宫动脉血流(uterineartery,UtA)动力学系统相关指标的观察，了解月经周期的黄体期及孕10周内UtA动力学特点及其对妊娠结局的影响。方法：将既往无不良妊娠史的育龄期妇女250例及既往有3次及以上的自然流产史妇女168例进行月经周期的排卵后及孕10周内经阴道超声监测双侧子宫动脉血流动力学参数，分别为:S/D^ft缩期峰值流速(S)/舒张末期流速(D)。阻力指数(Rl)=S-D/S；记录各组的Rl,S/D,对照统计各组子宫动脉Rl、S/D值及妊娠丢失率的差异。结果：1.孕前后或孕后子宫动脉血流异常者与正常者相比较，妊娠结局有显著性差异(P<0.05)2.孕前后或孕后子宫动脉血流值异常者未治疗与治疗后孕10周内恢复正常者Rl、S/D及妊娠丢失率均有统计学意义(P<0.05)3.RSA患者孕前异常血流纠正后，孕后子宫动脉血流异常率降低及其孕后异常血流治疗恢复率升高，与孕前未纠正者相比较，有统计学差异(P<0.05)o结论：1.孕早期子宫动脉血流参数与妊娠结局有相关性。2.异常血流早期纠正，能显著改善妊娠结局。3.RSA患者孕前子宫动脉血流参数影响妊娠结局。［关键词］:子宫动脉血流参数；早期妊娠；彩色多普勒超声；复发性流产；妊娠不良结局BeforepregnancyrelatedresearchafteruterinearterybloodflowchangesandpregnancyoutcomesWanglilGengShunling2FuJinhua3(1,3WeifangPeople'sHospital,WeifangShandong261041,China)Correspondingauthor:FuJinhua[Abstract]AIM:Toobservethe10weeksoftheuterinearterybloodflow(uterineartery,UtA)dynamicalsystemsrelatedindicatorsofreproductiveagethroughthe---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---normalandrecurrentmiscarriageforwomen(RecurrentSpontaneousAbortion,RSA)preparedamonthbeforepregnancyandafterpregnancyunderstandthelutealphaseofthemenstrualcycleandpregnancy10weeksUtAdynamicsandimpactonpregnancyoutcome.METHODS:Afternoprevioushistoryofadversepregnancywomenofchildbearingageandprevioushistoryofthreetimesandover250casesofspontaneousabortion(RSA)168casesofwomeninthemenstrualcycleandovulationcarriedout10weeksofpregnancybytransvaginalultrasoundmonitoringofuterinearterybloodhemodynamicparameters,namely:Resistanceindex(Rl)=S-D/S;S/D=peaksystolicvelocity/diastolicvelocity.Rlrecordsineachgroup,S/D,statisticaldifferencesbetweenthegroupsincontrolofuterinearteryRlvalue,S/Dvalueandpregnancylossrate.RESULTS:1,pre-pregnancy,abnormaluterinearterybloodflowcomparedwithnormalpregnancyoutcomesweresignificantdifferences(P<0.05)2,pregnancy,uterinearterybloodflowvalues??orpregnancyaftertreatmentandaftertreatmentisnotabnormalpregnancyreturnedtonormalafter10weeks,RlandS/Dandpregnancylossratewasstatisticallysignificant(P<0.05)3,RSApatientsaftercorrectingabnormalbloodpregnancy,afterpregnancyabnormaluterinearterybloodflowwassignificantlyreducedandtreatmenttorestorebloodflowabnormalitiesafterpregnancyrateincreased,comparedwiththepre-pregnancywerenotcorrected,therewassignificantdifference(P<0.05).CONCLUSION:1trimesteruterinearterybloodflowparameterscorrelatedwithpregnancyoutcomes.2.Earlycorrectingabnormalbloodflow,cansignificantlyimprovepregnancyoutcomes.3.RSAuterinearterybloodflowparametersinpatientswithpre-pregnancyaffectpregnancyoutcome.[Keywords]:Uterinearterybloodflowparameters;earlypregnancy;ColorDopplerultrasound;recurrentspontaneousabortion;poorpregnancyoutcomes【中图分类号】R473.2【文献标识码】A【文章编号】1001-5213...