南宁市近五年出生缺陷监测分析与干预措施探讨论着中外妇儿健康ChineseAndForeignWomenHealth2011年1月第19卷第1期南宁市近五年出生缺陷监测分析与T-预措施探讨龙忆琴【］R722.1【文献标识码】A【］1672-6383-（2011）01-0010-05【摘要】目的:进一步掌握南宁市出生缺陷的发生情况，分布特征，探索影响岀生缺陷的因素，为政府部门制订预防出生缺陷决策提供依据.方法:按《中国妇幼卫生监测方案》的要求，采用以医院为基础的监测方案，对2005〜2009年南宁市各医院进行出生缺陷监测，采用Excel软件进行数据录入,SPSS17.0软件包进行统计学分析.结果：南宁市2005〜2009年出生缺陷发生率有上升趋势（=250.245P=0・000《0.o6）平均发生率为15.81go;出生缺陷前6位类型依次为:胎儿水肿综合症，多指（趾）洗夭性心脏病，马蹄足内（外）翻，总唇腭裂，外耳畸形;城镇的出生缺陷发生率是20.04%。,显着高于乡村出生缺陷发生率（13.51%。）;缺陷儿产母年龄大于35岁，出生缺陷发生率明显增高(23.36go);缺陷儿中男耍发生率为16.83go明显高于女婴13.76%o；双胎出生缺陷儿发生率90.89%o显着高于单胎出生的缺陷儿15.16%。;出生缺陷产前诊断率逐年增---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---多2009年为46.01•结论:出生缺陷严重影响儿童的生存，健康和发展，因此,加强出生缺陷的一级预防即加强婚检宣教，做好孕前保健,孕早期保健,二级预防即全面产前筛查与高危孕妇的产前诊断，三级预防即新生儿体检，疾病筛查等，有效地降低出生缺陷的发生,降低围产儿死亡率.【关键词】出生缺陷;发生率;监测;干预措施MonitoringofbirthdefectsinrecentfiveyearsinNanningcityanalysisandinterventionmeasuresLongYi—qin[Abstract]Objective:FurthergraspstheNanningbirthdefecttheoccurrencesituation,thedistributioncharacteristic,theexplorationinflu一encebirthdefectfactor,drawsupthepreventionbirthdefectdecision一makingfortheGovernmentdepartmenttoprovidethebasis.Method:Ae一cordingto^ChinaWomen^andchildren^shygieneMonitorPlan^therequest,usestakethehospitalasthefoundationmonitorplan,carriesonthebirthdefectmonitorto2005〜2009yea「Nanningvarioushospitals,usestheExcelsoftwaretocarryonthedataentry,theSPSS17.0softwarepackagescarriesonstatisticsanalysis.Results:2005to2009,NanningCity,theincidenceofbirthdefectsinanupwardtrend(Y=250.245P=0.000《0.05)theaverageratewasl5.81%o；befbrethesixtypesofbirthdefectswere:fetaledemasyndrome,multiplefingers(toes),con一---本文于网络，仅供参考，勿照抄，如有侵权请联系删除---genitalheartdisease,clubfoot(outside)turn,thetotalcleftlipandpalate,eardeformities;townstheincidenceofbirthdefectswas20.04%o?significantlyhigherthanruralincidenceofbirthdefects(13.51go);defectsproducedChildrenagedmotherniorethan35yearsofage,theinci一denceofbirthdefectswassigniflcantlyhigher(23.36,i0);defectsinmalechildrenwas16.83%0,Significantlyhigherthangirls13.76%口;twinstheincidenceofbirthdefectsinchildrenwassignificantlyhigherthan90.89%ofetalbirthdefectsinasinglechild15.lG^^ojateof^wnataldiag—nosisofbirthdefectsincreasedyearbyyearto46.0lin2009.Conclusions:seriousinfluenceonchildren^birthdefectsofsurvival,developmentandhealthybirthdefects,therefore,tostrengthentheprimarypreventionnamelstrengtheningcheck-upsmission,pregnantcare,healthcare,thesecondarypreventioninearlypregnancyispregnantwithcomprehensiveantenatalscreeninghigh—riskprenataldiagnosis,preventionisinedi一calscreeningnewborns,diseaseetc,effectivelyreducebirthdefects,reduceperinatalmortality.[Keywords]Incidenceofbirthdefectsmonitoringinterventionmeasures提高出生人口素质,降低出生缺陷发生率，是《中华人民共和国母婴保健法》及《中华人民共和...