中山大学学报(医学科学版)JOURNALOFSUNYAT-SENUNlVERSnvY(MEI)lCALSCIENCES)•Editoriaol•PerspectiveonMetabolicSyndromeinChinaNormanC・W・WONG1,XIAOHai-peng2(1.DepartmentofMedicineandBiochemistry&MolecularBiology>LibinGeneTherapyUnit,FacultyofMedicine,UniversityofCalgary,HealthSciencesCenter,Alberta,Canada,T2N4N1;2.DepartmentofEndocrinology,TheFirstAfTilialedHospital,SUNYat-senUniversity,Guangzhou510080,China)Abstract:MetabolicsyndromeisontheriseinChina.AnimprovedunderstandingofthecriteriaforthediagnosisofthissyndromewillleadloimportantquestionsforthepopulationinChina.Theprogressionofthissyndromelotype2diabetesmellitus(DM)isadreadedoutcomethatmaybeprevented.OnceDMisestablished^knowledgeofthecurrenttherapeuticapproachesisrequired.Keywords：metabolicsyndrome;diagnosiscriteria;preventionCLCnumber:R58Documentcode:AArticleID:1672-3554(2005)01-0001-03中国人的代谢综合征研究展望NormanC.W.WONG\肖海鹏2(1.加拿大卡加利大学医学中心内科学、生物化学与细胞生物学〃Libin基因治疗中心，艾伯塔加拿大，T2N4N1;2.中山大学附属第一医院内分泌科，广东广州，510080)摘要:代谢综合征在中国正不断上升•提高对这一综合征诊断标准的认识，将对中国人代谢综合征的防治有重要意义。代谢综合征进展为2型糖尿病是一个令人担忧的结局,但幸运的是这一进程是可预防的。一旦糖尿病的诊断确立,则应用现代的防治手段进行干预。关键词:代谢综合征；诊断标准；预防IJSUNYat-wnUniv(MedSci)t2005.26⑴：l-3|---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---第26卷第1期2005年1月Vol.26No.lJan.2005---本文来源于网络，仅供参考，勿照抄，如有侵权请联系删除---Thediagnosisofmetabolicsyndrome(MS)isdefinedbyacollectionofbothclinicalandbiochemicalcriteria吧MSisnotanewsyndromebecauseitsinitialdescriptioncanbetracedbackto1923RenewedinterestinthesyndromestemsfromtherisingprevalenceofthissyndromeandReavenzsdefinitionin1988ofsocalledsyndromeX⑹.TheapplicationofdiagnosticcriteriatodetenninethepresenceofMSinpatientsprovidesacluelounderlyingorimpendingcardiovasculardisease9TheepidemicriseinthenumberofpatientswithMSisaffectingthehealthofpopu・lationsnotonlyinNorthAmericabutthroughouttheworldsThepurposeofthisreviewistopromotedis-cussionandlohighlighttheimportanceofMSinpopulationofChina.WehopethisbriefpresentationwillhelprefreshourmemoryofpreviousandhelpidentifynewquestionsthatmayprovidetheseedforfuturestudiesofMSinthepopulationofChina.ThemajorityoftheinformationusedtobuildthedefinitionofMScomesfrompublishedstudiescompletedinNorthAmericaandEurope.ThisisnotmeanttobeacriticismofthecriteriathatareusedtodefineMSaccordingtoguidelinesissuedfromvarioushealthorganizations(WHO,NCEP-ATPIIIorESD)buttounderstandtheirorigin.TheapplicationoftheslightlydifferentcriteriaforthediagnosisofMSunderliesthevariableestimatesofMSinagivenpopulation・Forexample,theuseofabdominalgirthisoneoftheATP-IIIcriteriaforthediagnosisofMSbuttheuseofthismeasurementintheChinesepopulationmayunderestimatethenumbersofpatientswithMSbecauseofphysiologicdifferencesbetweentheChineseandNorthAmericanpopulation.Inrecognitionofthislimitation,therecentMScriteriaproposedbytheChinesediabetesassociateproposetheuseofaBMIof25門Althoughthisdifferencewillcertainlybypasstheissueofabdominalgirth,itmaydefineahigherthresholdforthediagnosisofMSinfemalepopulationversusthatinmales.Inaddition,theslightlyhigherbloodpressurelimitsof140/90mmHgforsystolicanddiastolicBP,respectivelyisanotherslightdiff...